Yu Liu

BACKGROUND: To address the clinical features and potential risk factors of ovarian pregnancy (OP). METHODS: In this retrospective case-control study performed in West China Second University Hospital from March 17, 2005 to December 8, 2018…

BACKGROUND: Acute myeloid leukemia (AML) patients with normal karyotype (NK-AML) have significant variabilities in outcomes. The European Leukemia Net stratification system and some prognostic models have been used to evaluate risk stratifi…

Women with diminished ovarian reserve (DOR) have reduced fertility, but the underlying regulation of ovarian function remains unknown. Although differential microRNA (miRNA) expression has been described in several ovarian disorders, little…

N6-methyladenosine (m6A) is the most prevalent chemical modification in eukaryotic messenger RNAs. By participating in various RNA-related bioprocesses including RNA decay, splicing, transport and translation, m6A serves as a pivotal regula…

Infertile women with diminished ovarian reserve (DOR) confront an increased miscarriage rate in assisted reproductive technology (ART). Genetic abnormality is the most important factor. However, the effects of DOR and female age on the mole…

Ovarian cancer (OC) remains the leading cause of mortality due to gynecological malignancies. Epidemiological studies have demonstrated that steroid hormones released from the hypothalamic‑pituitary‑ovarian axis can play a role in stimulati…

BACKGROUND: Endometriosis, the presence of active endometrial tissue outside the lining membrane of the uterine cavity, is a common disease in women of childbearing age. The ectopic endometrium has some characteristics of tumor tissue, incl…

To summarize the clinical features, diagnosis, and treatments of perineal endometriosis (PEM).We retrospectively studied the clinical data of 35 patients with PEM between April 2012 and December 2018 in West China Second Hospital. Patients …

Extracellular vesicles (EVs), present in cell culture media and several body fluids, play a prominent role in intercellular communication under physiological and pathological conditions. We performed a systematic literature search to review…

Recently, a growing body of evidence has suggested that abnormal ovarian angiogenesis, secondary to the imbalance between various angiogenic markers, is involved in the pathogenesis of PCOS, and this has led to the use of various interventi…

Recently, the research on early detection of precancerous change and endometrial carcinoma has been focusing on minimally invasive procedures for screening. On this basis, we aim to verify the feasibility of endometrial samplers for screeni…

BACKGROUND: Female reproductive tumors are common with high morbidity and mortality worldwide; however, the association between gynecological tumors and serum vitamin D is controversial. The aim of this meta-analysis was to evaluate the rel…

To improve the release profile of peptide drugs, thermos-responsive triblock copolymer poly (ε-caprolactone-co-p-dioxanone)-b-poly (ethylene glycol)-b-poly (ε-caprolactone-co-p-dioxanone) (PECP) was prepared and end capped by succinic anhyd…

Objective To investigate the effect of vasopressin injection technique on ovarian reserve in patients with laparoscopic cystectomy of unilateral ovarian endometrioma. Methods 70 patients with unilateral ovarian endometrioma were rand…

Lack of mucoadhesive properties is the major drawback to poloxamer 407 (F127)-based in situ hydrogels for mucosal administration. The objective of the present study was to construct a novel mucoadhesive and thermosensitive in situ hydrogel …

OBJECT: Reproductive system related autoantibodies have been proposed to be associated with natural infertility. However, large scale systematic analysis of these of antibodies has not been conducted. The aim of this study is to analyze the…

Objective To observe the effect of compound Rhizoma Curcumae power on the expression of p21 in ectopic and eutopic endometria in patients with ovarian endometriosis cyst( chocolate cyst). Methods A total of 69 patients with chocolate cyst w…

Objective To explore a stage Ⅲ～Ⅳ endometriosis after conservative surgery in patients with recurrence rates and related factors.Methods Retrospective analysis of stage Ⅲ-Ⅳ underwent conservative surgery for endometriosis in patients with cl…

Objective To investigate the clinical characteristics,diagnosis,treatment of endometriosis in adolescent and to improve our knowledge,and to reduce misdiagnosis.Methods Clinical data of 17 patients with endometriosis in adolescents were ana…

Objective To investigate the expression of hepatocyte growth factor (HGF) and C Met in the eutopic endometrium of pelvic endometriosis and the relationship between HGF and C Met in the pathogenesis of endometriosis. Methods The expression o…