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This review focuses on the complex events that occur in the endometrium after progesterone is withdrawn (or blocked) and menstrual bleeding ensues. A detailed understanding of these local mechanisms will enhance our knowledge of disturbed e…
Progesterone is essential to the establishment and maintenance of pregnancy. Compounds that inhibit the synthesis of progesterone, or antagonize progesterone action, have multiple effects including the induction of abortion, labor induction…
Antigestogens are compounds which inhibit the synthesis of progesterone or antagonise its biological action. The progesterone antagonist mifepristone (RU 486) binds with high affinity to progesterone receptors throughout the body, blocking …
What is the current state of clinical application of inhibition of gonadal activity with LHRH agonists or antagonists? It seems unlikely in the short term that antagonists will be widely applied due to the short-acting nature of the present…
Many control applications, including feedforward and learning control, involve the inverse of a dynamical system. For nonminimum-phase systems, the response of the inverse system is unbounded. For linear time-invariant (LTI), nonminimum-pha…