Chen LX

No ORCID on file · 6 papers in corpus · active 2016-2023

Study types

  • article 1

Condition tags

  • dysmenorrhea 1
  • endometriosis 1
  • chronic_pelvic_pain 1
  • infertility 1
  • dyspareunia 1
2023
Association between maternal MTHFR C677T/A1298C combination polymorphisms and IVF/ICSI outcomes: a retrospective cohort study.
Human reproduction open ·doi:10.1093/hropen/hoac055

Study questionWhat are the roles of maternal 5,10-methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C combination polymorphisms on the embryological and clinical outcomes of IVF/ICSI?Summary answerOur study reveals for the first time t…

2021
Analysis of related factors affecting cumulative live birth rates of the first ovarian hyperstimulation in vitro fertilization or intracytoplasmic sperm injection cycle: a population-based study from 17,978 women in China.
Chinese medical journal ·doi:10.1097/cm9.0000000000001586

BackgroundMore and more scholars have called for the cumulative live birth rate (CLBR) of a complete ovarian stimulation cycle as a key indicator for assisted reproductive technology. This research aims to study the CLBR of the first ovaria…

2018
Comparison of Vaginal Gel and Intramuscular Progesterone for In vitro Fertilization and Embryo Transfer with Gonadotropin-Releasing Hormone Antagonist Protocol.
Chinese medical journal ·doi:10.4103/0366-6999.235106

BackgroundLuteal support is a key to patients undergoing in vitro fertilization and embryo transfer (IVF-ET) with gonadotropin-releasing hormone (GnRH)-antagonist protocol. This study aimed to compare the effect between vaginal progesterone…

2018
Estrogen-regulated miRNA-27b is altered by bisphenol A in human endometrial stromal cells.
Reproduction (Cambridge, England) ·doi:10.1530/rep-18-0041

MicroRNAs (miRs) are small molecules important for regulation of transcription and translation. The objective was to identify hormonally regulated miRs in human endometrial stromal cells and to determine the impact of the endocrine disrupto…

2016
Barcoded sequencing reveals diverse intrauterine microbiomes in patients suffering with endometrial polyps.
American journal of translational research

Results of this study showed that the bacterial composition in vagina (V) greatly differed from intrauterine microbiome (I). Microbiomes were present in all intrauterine samples of healthy women (Group H (I)) and patients with endometrial p…

article 2016
Overexpression of chloride channel-3 is associated with the increased migration and invasion ability of ectopic endometrial cells from patients with endometriosis
Human Reproduction ·doi:10.1093/humrep/dew034

STUDY QUESTION: Is chloride channel-3 (ClC-3) involved in regulating the biological behavior of endometrial stromal cells (ESCs)? SUMMARY ANSWER: ClC-3 promotes endometriotic cell migration and invasion. WHAT IS KNOWN ALREADY: ClC-3 plays a…