Serdar E Bulun
No ORCID on file
· 126 papers in corpus
· active 1996-2025
Study types
- article 69
- review 33
- other 11
- book-chapter 7
- letter 4
Condition tags
- endometriosis 106
- infertility 14
- chronic_pelvic_pain 7
- adenomyosis 6
- dyspareunia 1
- mesh:D004716 1
- endometrioma 1
- dysmenorrhea 1
Top journals
Frequent coauthors
- Bulun SE 71
- Mary Ellen Pavone 28
- Bilgin Gürateş 24
- Matthew T. Dyson 22
- Ping Yin 20
- You-Hong Cheng 16
- Sijun Yang 15
- Mitsutoshi Tamura 15
- Gurates B 15
- Zong Juan Fang 15
article
2018
Steroidogenic factor-1 (SF-1, encoded by NR5A1) and estrogen receptor beta (ERβ, encoded by ESR2), which are highly expressed in endometriotic stromal cells (ESCs), contribute to the pathogenesis of endometriosis, but the regulation mechani…
article
2018
article
2017
Decidualization alters multiple molecular pathways in endometrium to permit successful embryo implantation. We have reported that paracrine factors, including retinoids, secreted from progesterone-treated endometrial stromal cells, act on n…
letter
2016
other
2016
OBJECTIVE: To determine the expression and biological roles of serum and glucocorticoid-regulated kinase (SGK1) in tissues and cells from patients with endometriosis and from healthy control subjects. DESIGN: Case-control. SETTING: Univer…
article
2016
ObjectiveFenretinide is a synthetic retinoid analogue that promotes apoptosis but has decreased toxicity when compared to other retinoids. We have previously shown that retinoic acid (RA) production in endometriotic tissue is decreased, res…
article
2016
Endometriosis is a gynecological disease defined by the extrauterine growth of endometrial-like cells that cause chronic pain and infertility. The disease is limited to primates that exhibit spontaneous decidualization, and diseased cells a…
article
2016
Steroidogenic factor 1 (SF-1), a transcriptional factor essential for estrogen biosynthesis, is undetectable in endometrial stromal cells and aberrantly expressed in endometriotic stromal cells.Objective:We tried to gain further insight int…
article
2015
ObjectiveTo define the expression and function of DNA methyltransferases (DNMTs) in response to decidualizing stimuli in endometriotic cells compared with healthy endometrial stroma.DesignBasic science.SettingUniversity research center.Pati…
review
2015
Endometriosis has been initially described as the presence of ectopic endometrial tissue on pelvic organs or in extrapelvic sites; and this has been used as its key pathologic feature ever since. Endometriosis responds to fluctuations in es…
article
2015
article
2014
In endometriosis, stromal and epithelial cells from the endometrium form extrauterine lesions and persist in response to estrogen (E2) and prostaglandin E2 (PGE2). Stromal cells produce excessive quantities of estrogen and PGE2 in a feed-fo…
article
2014
article
2014
Endometriosis is a gynecological disease defined by the extrauterine growth of endometrial-like cells that cause chronic pain and infertility. The disease is limited to primates that exhibit spontaneous decidualization, and diseased cells a…
other
2014
UNLABELLED: Steroidogenic factor 1 (SF-1), a transcriptional factor essential for estrogen biosynthesis, is undetectable in endometrial stromal cells and aberrantly expressed in endometriotic stromal cells. OBJECTIVE: We tried to gain furt…
letter
2014
article
2013
In stromal cells of endometriosis, marked levels of aromatase P450 (P450arom) mRNA and activity are present and can be vigorously stimulated by (Bu) 2cAMP or PGE 2 to give rise to physiologically significant estrogen biosynthesis. Since eut…
review
2013
Our guest editor, Dr. Dan Lebovic, is a world-renowned physician-scientist and reproductive endocrinologist who has dedicated his career to studying the molecular and translational aspects of endometriosis. His impressive published body of …
review
2013
Progesterone receptor (PR) mediates the actions of the ovarian steroid progesterone, which together with estradiol regulates gonadotropin secretion, prepares the endometrium for implantation, maintains pregnancy, and differentiates breast t…
review
2013
CONTEXT: Anovulation is likely responsible for 20% of female infertility. Although clomiphene citrate remains the first-line therapy for ovulation induction in anovulatory patients who are not estrogen-deficient and to treat unexplained inf…
other
2012
OBJECTIVE: To define altered gene expression networks in endometriosis. DESIGN: Experiments using endometriotic tissues and primary cells. SETTING: Division of Reproductive Biology Research, Northwestern University. PATIENT(S): Premenopa…
review
2012
ObjectiveTo review the use of aromatase inhibitors (AIs) for the treatment of endometriosis.DesignLiterature review.Conclusion(s)Most studies show that in reproductive-age women, the combination of AI with conventional therapy alleviates en…
article
2012
ObjectiveTo determine the effect of inhibiting aromatase activity on endometrial lesion growth and aromatase expression in a baboon model of induced endometriosis.DesignProspective study.SettingPrimate research institute.Animal(s)Sixteen ol…
letter
2012
article
2012