Chen SL

No ORCID on file · 11 papers in corpus · active 1988-2025

Study types

  • article 3
  • other 1
  • review 1

Condition tags

  • endometriosis 5
  • infertility 2
  • endometrioma 1
review 2025
Targeting ferroptosis for the treatment of female reproductive system disorders
Journal of molecular medicine (Berlin, Germany) ·doi:10.1007/s00109-025-02528-x

Ferroptosis, a regulated form of cell death driven by iron-dependent lipid peroxidation, has emerged as a critical factor in female reproductive health and has been implicated in disorders such as polycystic ovary syndrome, premature ovaria…

2024
USP14 inhibition promotes DNA damage repair and represses ovarian granulosa cell senescence in premature ovarian insufficiency.
Journal of translational medicine ·doi:10.1186/s12967-024-05636-3

BackgroundPremature ovarian insufficiency (POI) is a condition characterized by a substantial decline or loss of ovarian function in women before the age of 40. However, the pathogenesis of POI remains to be further elucidated, and specific…

2023
Elevated cell-free mitochondria DNA level of patients with premature ovarian insufficiency.
BMC pregnancy and childbirth ·doi:10.1186/s12884-023-05769-1

BackgroundPremature ovarian insufficiency (POI) patients present with a chronic inflammatory state. Cell-free mitochondria DNA (cf-mtDNA) has been explored as a reliable biomarker for estimating the inflammation-related disorders, however, …

2023
Plasma metabolomic characterization of premature ovarian insufficiency.
Journal of ovarian research ·doi:10.1186/s13048-022-01085-y

BackgroundPremature ovarian insufficiency (POI) patients are predisposed to metabolic disturbances, including in lipid metabolism and glucose metabolism, and metabolic disorders appear to be a prerequisite of the typical long-term complicat…

2020
Intramuscular injection of human chorionic gonadotropin prior to secretory transformation in patients undergoing frozen-thawed embryo transfer cycles.
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-020-00606-y

BackgroundThe major difference between a natural cycle and an artificially prepared cycle is the lack of luteinizing hormone (LH) peak in the latter. The LH/hCG receptors were identified to express in human endometrium and evidences of expe…

article 2018
Down-regulation of long non-coding RNAMALAT1inhibits granulosa cell proliferation in endometriosis by up-regulating P21 via activation of the ERK/MAPK pathway
Molecular human reproduction ·doi:10.1093/molehr/gay045

STUDY QUESTION: Is there a specific mechanism underlying the association between lung adenocarcinoma transcript 1 (MALAT1) and endometriosis-related infertility? SUMMARY ANSWER: The down-regulation of MALAT1 in endometriosis granulosa cells…

2014
Follicular fluid Aβ40 concentrations may be associated with ongoing pregnancy following in vitro fertilization.
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-014-0345-6

PurposeTo determine whether Aβ40 levels in the follicular fluid (FF) of infertile women undergoing IVF demonstrate a relationship with IVF cycle parameters and outcome.MethodsFF Aβ40 levels were compared between patients achieving ongoing p…

article 2013
Ovarian damage after laparoscopic endometrioma excision might be related to the size of cyst
Fertility and sterility ·doi:10.1016/j.fertnstert.2013.03.033

ObjectiveTo investigate the relationship between the size of an excised endometrioma and the magnitude of damage to the ovary after the surgery.DesignA retrospective, controlled study.SettingA university hospital.Patient(s)Eighty-five women…

2010
Combined analysis of endometrial thickness and pattern in predicting outcome of in vitro fertilization and embryo transfer: a retrospective cohort study.
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-8-30

ObjectiveTo evaluate the combined effect of endometrial thickness and pattern on clinical outcome in patients undergoing in vitro fertilization/intracytoplasmic sperm injection and embryo transfer (IVF/ICSI-ET).MethodsCycles of IVF/ICSI-ET …

article 2002
Expression of trophinin in the cycling endometrium and its association with infertility.
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA

OBJECTIVE: To observe the expression of trophinin in the cycling endometrium and investigate its relationship with infertility. METHODS: Trophinin expression in the endometrium was observed in 39 normal cycling women during different menstr…

other 1988
Serum and peritoneal lavage fluid CA-125 levels in endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(16)60127-9

Serum and peritoneal lavage fluid CA-125 levels were assayed in 20 women with endometriosis and 20 control women at the time of laparoscopy. Serum levels of CA-125 were significantly higher in women with endometriosis. Peritoneal lavage flu…