Reiner Strick

Endometriosis is a chronic disease of women in the reproductive age, defined as endometrial cells growing outside of the uterine cavity and associated with relapses. Relapses are hypothesized to correlate with incomplete surgical excision o…

Background: In the pathogenesis of endometriosis adhesions play a major role. Applying adhesion barrier on the peritoneal wound that might act as a seeding ground could also prevent endometrial cells to adhere, invade and grow and thus caus…

Question: Ulipristalacetate (UPA) has been previously demonstrated to inhibit the estradiol and progesterone induced proliferative response of normal endometrial cells in culture. We predicted that UPA would inhibit proliferation of endomet…

We identified differentially expressed genes comparing peritoneal endometriosis lesions (n = 18), eutopic endometrium (n = 17), and peritoneum (n = 22) from the same patients with complete menstrual cycles using microarrays (54 675 probe se…

ObjectiveTo investigate whether sexually transmitted viruses or prokaryotes, like human papilloma viruses (HPV), herpes viruses, and Chlamydia trachomatis, are associated with endometriosis lesions.DesignSixty-six endometriosis lesions from…

Research involving estrogen and progesterone receptors (ER and PR) have greatly contributed to our understanding of cell signaling and transcriptional regulation. In addition to the classical ER and PR nuclear actions, new signaling pathway…

BACKGROUND: None of the existing theories provides a satisfactory explanation of the development of endometriosis. One hypothesis that may lead to further clarification is that the expression of specific proteins of human endogenous retrovi…

INTRODUCTION: Dysmenorrhoea is the major symptom in women with endometriosis. Recently, pain modulation through Neurokinin-1-receptor (NK1R) pathways have been investigated in neuropathic pain patients. Aim of this study was, therefore, to …

OBJECTIVE: Uterine benign leiomyomas result from proliferation of a single smooth-muscle cell and their growth is affected by steroid hormones via steroid hormone receptors. This investigation analyzed the +331G/A and the V600L single nucle…

OBJECTIVE: The objective of the present study was to evaluate the correlation between anti-müllerian hormone (AMH), inhibin B, and activin A in follicular fluid from patients receiving treatment with in-vitro fertilization (IVF) and intracy…

Hintergrund und Ziele Der Grund für die Entstehung der Endometriose, als spezifische Erkrankung des Endometriums ist bis heute ungeklärt. Diskutiert werden verschiedenste Mechanismen, wie die Transplantationstheorie nach Sampson, die Metapl…

Hintergrund: Endometriose ist eine chronisch inflammatorische Erkrankung mit einer Inzidenz von bis zu 30%. Trotz hoher Prävalenz ist die Ätiologie der Endometriose weitgehend unverstanden. Neben peritonealen Faktoren werden Veränderungen d…

Endometriosis is a chronic inflammatory disease, which is especially found in women with subfertility problems with an incidence of up to 30%. The disease is considered an estrogen-dependent disorder, where DNA polymorphisms of the estrogen…