Hsieh JC

No ORCID on file · 9 papers in corpus · active 2013-2023

Condition tags

  • dysmenorrhea 7
2023
Adaptive neuroplasticity in the default mode network contributing to absence of central sensitization in primary dysmenorrhea.
Frontiers in neuroscience ·doi:10.3389/fnins.2023.1094988

IntroductionPrimary dysmenorrhea (PDM), the most prevalent gynecological problem among women of reproductive age, presents as a regular pattern of cyclic menstrual pain. The presence or absence of central sensitization (i.e., pain hypersens…

2021
Neuroprotective effect of Val variant of BDNF Val66Met polymorphism on hippocampus is modulated by the severity of menstrual pain.
NeuroImage. Clinical ·doi:10.1016/j.nicl.2021.102576

Primary dysmenorrhea (PDM) refers to menstrual pain of which the pathological cause(s) are unknown. This study examined the associations among BDNF Val66Met polymorphisms, menstrual pain severity, and hippocampal volume among young PDM subj…

2018
Unaltered intrinsic functional brain architecture in young women with primary dysmenorrhea.
Scientific reports ·doi:10.1038/s41598-018-30827-6

Primary dysmenorrhea (PDM), painful menstruation without organic causes, is the most prevalent gynecological problem in women of reproductive age. Dysmenorrhea later in life often co-occurs with many chronic functional pain disorders, and c…

2017
Encoding of menstrual pain experience with theta oscillations in women with primary dysmenorrhea.
Scientific reports ·doi:10.1038/s41598-017-16039-4

Theta oscillation (4-7 Hz) is well documented for its association with neural processes of memory. Pronounced increase of theta activity is commonly observed in patients with chronic neurogenic pain. However, its association with encoding o…

2017
The OPRM1 A118G polymorphism modulates the descending pain modulatory system for individual pain experience in young women with primary dysmenorrhea.
Scientific reports ·doi:10.1038/srep39906

The mu-opioid receptor (OPRM1) A118G polymorphism underpins different pain sensitivity and opioid-analgesic outcome with unclear effect on the descending pain modulatory system (DPMS). Primary dysmenorrhea (PDM), the most prevalent gynecolo…

2016
Dynamic Changes of Functional Pain Connectome in Women with Primary Dysmenorrhea.
Scientific reports ·doi:10.1038/srep24543

Primary dysmenorrhea (PDM) is the most prevalent gynecological problem. Many key brain systems are engaged in pain processing. In light of dynamic communication within and between systems (or networks) in shaping pain experience and behavio…

2016
The BDNF Val66Met polymorphism is associated with the functional connectivity dynamics of pain modulatory systems in primary dysmenorrhea.
Scientific reports ·doi:10.1038/srep23639

Primary dysmenorrhea (PDM), menstrual pain without an organic cause, is a prevailing problem in women of reproductive age. We previously reported alterations of structure and functional connectivity (FC) in the periaqueductal gray (PAG) of …

2014
Association of brain-derived neurotrophic factor gene Val66Met polymorphism with primary dysmenorrhea.
PloS one ·doi:10.1371/journal.pone.0112766

Primary dysmenorrhea (PDM), the most prevalent menstrual cycle-related problem in women of reproductive age, is associated with negative moods. Whether the menstrual pain and negative moods have a genetic basis remains unknown. Brain-derive…

2013
Large chromosome deletions, duplications, and gene conversion events accumulate with age in normal human colon crypts.
Aging cell ·doi:10.1111/acel.12053

Little is known about the types and numbers of mutations that may accumulate in normal human cells with age. Such information would require obtaining enough DNA from a single cell to accurately carry out reliable analysis despite extensive …