Marsh EE

ObjectiveTo compare IVF utilization rates and IVF outcomes in states with and without mandates for male infertility coverage. In 2020, 43 states recorded their lowest fertility rate in 3 decades. In-vitro fertilization (IVF) is an important…

BackgroundPrior studies show that people with larger bodies experience pervasive weight stigma, which is often directly perpetuated by healthcare providers. This pattern has also been observed in women receiving prenatal and postpartum care…

The human uterus is a complex and dynamic organ whose lining grows, remodels, and regenerates every menstrual cycle or upon tissue damage. Here, we applied single-cell RNA sequencing to profile more the 50,000 uterine cells from both the en…

Objective: To compare 12-month post-treatment health-related quality of life (HR-QoL) and symptom severity (SS) changes among patients with symptomatic uterine fibroids (SUF) not seeking fertility and undergo a hysterectomy, abdominal myome…

Research questionAre gravidity, parity and breastfeeding history associated with anti-Müllerian hormone concentration among African-American women of reproductive age?DesignThis study included baseline data from the Study of the Environment…

ObjectiveTo understand healthcare experiences among patients with uterine fibroids (fibroids) across the continuum of care, from early symptoms through diagnosis, treatment, and management, while also investigating health disparities.Method…

Fallopian tube (FT) homeostasis requires dynamic regulation of heterogeneous cell populations and is disrupted in infertility and ovarian cancer. Here, we applied single-cell RNA-seq to profile 59,738 FT cells from four healthy, pre-menopau…

OBJECTIVE: To compare the proteomic composition of follicular fluid from women with normal weight vs. women with obesity but without a history of polycystic ovary syndrome or known ovarian dysfunction undergoing in vitro fertilization. DES…

PurposeTo report experience designing and establishing a reproductive registry and sample biorepository and to describe initial subject characteristics and biospecimens.MethodsBeginning in December 2017, patients presenting for reproductive…

Women's health concerns are generally underrepresented in basic and translational research, but reproductive health in particular has been hampered by a lack of understanding of basic uterine and menstrual physiology. Menstrual health is an…

Ovarian reserve refers to the number of oocytes remaining in a woman's ovaries that have the potential to yield a pregnancy. This is a concept based on the fact that the number of oocytes within a woman's ovaries and her ability to achieve …

ObjectiveTo compare short-term health-related quality of life (HRQOL) 6-12 weeks after hysterectomy or myomectomy for the treatment of symptomatic leiomyomas.MethodsWe conducted a prospective comparative effectiveness analysis of data. In a…

BackgroundMost women will experience uterine fibroids by the age of 50, yet few data exist describing the overall patient experience with fibroids. The objective of this population-based survey was to characterize symptom burden, patient aw…

BackgroundUterine fibroids are common in premenopausal women, yet comparative effectiveness research on uterine fibroid treatments is rare.ObjectiveThe purpose of this study was to design and establish a uterine fibroid registry based in th…

ObjectiveTo characterize normative antimüllerian hormone (AMH) levels and ascertain which factors are associated with AMH in a large cohort of reproductive-age women.DesignCross-sectional study.SettingNot applicable.Patient(s)A total of 1,6…

ObjectiveTo assess self-reported prevalence, knowledge, and health literacy regarding heavy menstrual bleeding (HMB) among African American women.MethodsA quantitative cross-sectional survey study was conducted. An original survey was devel…

Estradiol (E2) stimulates the growth and inflammation in the ectopic endometriotic tissue that commonly resides on the pelvic organs. Several clinical and laboratory-based observations are indicative of resistance to progesterone action in …

ContextControl of aromatase expression in uterine leiomyoma has significant clinical implications because aromatase inhibitors reduce tumor growth and associated irregular uterine bleeding. The mechanisms that regulate aromatase expression …

ObjectiveTo identify endometriosis as a cause of chronic pelvic pain in premenarcheal girls without an obstructive anomaly of the reproductive tract.DesignA case series.SettingTertiary-care academic pediatric hospital.Patient(s)Five premena…