Toshihiro Aono — Endo Lab

article 2001

Efficacy of Every-Other-Day Administration of Conjugated Equine Estrogen and Medroxyprogesterone Acetate on Gonadotropin-Releasing Hormone Agonists Treatment in Women with Endometriosis

Gynecologic and obstetric investigation ·doi:10.1159/000052978

We performed a randomized controlled study to determine the efficacy of add-backed therapy by every-other-day administration of 0.625 mg conjugated equine estrogen (CEE) and 2.5 mg medroxyprogesterone acetate (MPA) on GnRH agonists (GnRH-a)…

article 1993

Induction of true precocious puberty by neonatal treatment with danazol in female rats

·doi:10.1016/0304-3940(93)90636-y

Female rats at 5 days of age were given a single subcutaneous injection of varying doses of danazol or vehicle. Rats treated with 300 micrograms of danazol showed significant (P < 0.01, respectively) advancement in the day of vaginal openin…

article 1991

Effects of nocturnal hyperprolactinemia on ovarian luteal function and galactorrhea

·doi:10.1016/0028-2243(91)90056-q

To determine the effects of nocturnal hyperprolactinemia on luteal function and galactorrhea we studied six diurnal normoprolactinemic women with regular menstrual cycles. The diurnal serum levels of prolactin (PRL), luteinizing hormone (LH…

article 1989

Studies on GnRH Agonist Suppression of Estrogen Production in Patients with Endometriosis.

Endocrinologia japonica ·doi:10.1507/endocrj1954.36.611

The chronic administration of GnRH agonists to women results in the reversible suppression of estrogen production by the ovary. In the present study, the mechanism of the GnRH agonist suppression of estrogen production was investigated in p…

article 1987

Growth inhibition by danazol in a human endometrial cancer cell line with estrogen-independent progesterone receptors

·doi:10.1016/0022-4731(87)90517-6

Since we recently found that danazol, an isoxazol derivative of ethinyltestosterone, has a growth-inhibitory effect on human endometrial cancer cells in primary culture, the effects of danazol on a human endometrial cancer cell line (IK-90 …

article 1986

Danazol binds to progesterone receptors and inhibits the growth of human endometrial cancer cells in vitro

·doi:10.1016/s0002-9378(86)80039-4

Based on our recent findings that danazol, an isoxazol derivative of ethinyltestosterone, has a profound growth-inhibitory effect on an established human endometrial adenocarcinoma cell line, the effects of danazol on cancer cells from huma…

article 1985

The effect of lisuride hydrogen maleate on anterior pituitary hormones, oestradiol and cortisol in normal and hyperprolactinaemic women

·doi:10.1016/0028-2243(85)90079-6

The effects of single oral doses of 0.1 mg lisuride hydrogen maleate (lisuride), a semisynthetic ergot derivative given at 09.00 h, on the serum levels of prolactin (PRL), luteinizing hormone (LH), follicle-stimulating hormone (FSH), growth…

article 1983

Absence of effect of danazol on estrogen-induced luteinizing hormone release from rat hypothalamo-pituitary axis in vitro

·doi:10.1016/s0010-7824(83)80009-2

The effects of danazol on luteinizing hormone (LH) release by estradiol (E2) were examined in a sequential double chamber superfusion system by superfusing the mediobasal hypothalamus (MBH) and pituitary excised from normal female rats in d…

article 1978

Clinical and Endocrinological Analyses of Patients with Galactorrhea and Menstrual Disorders due to Sulpiride or Metoclopramide

·doi:10.1210/jcem-47-3-675

The clinical courses of galactorrhea and menstrual disorders were studied in 18 women with galactorrhea induced by sulpiride (SLP) or metoclopramide (MCP) given for the treatment of gastrointestinal diseases. The response of PRL and TSH to …