Jing H

No ORCID on file · 4 papers in corpus · active 2024-2026
2026
CCDC174 deficiency impaired human fertility by affecting the alternative splicing of maternal mRNAs.
EMBO molecular medicine ·doi:10.1038/s44321-026-00448-y

Precise regulation of alternative splicing (AS) of maternal mRNAs is crucial for maintaining mRNA homeostasis and for acquiring oocyte competence. However, the regulatory factors and mechanisms of AS regulating oocyte competence and human f…

2026
Genetic landscape of human oocyte/embryo defects.
Cell genomics ·doi:10.1016/j.xgen.2025.101012

Oocyte/embryo defects can result in oocyte maturation arrest, fertilization failure, embryonic arrest, and infertility as well as recurrent in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) failures. However, the genet…

2025
The role of Akkermansia muciniphila in the regulation of inflammatory bowel disease: intestinal immunity and metabolism.
Frontiers in immunology ·doi:10.3389/fimmu.2025.1653472

Inflammatory bowel disease (IBD) is closely associated with the abundance of Akkermansia muciniphila (A. muciniphila), a resident member of the intestinal tract that is being developed as a next-generation probiotic. Accumulated evidence ha…

2024
Machine learning-based diagnostic model for preoperative differentiation between xanthogranulomatous cholecystitis and gallbladder carcinoma: a multicenter retrospective cohort study.
Frontiers in oncology ·doi:10.3389/fonc.2024.1355927

BackgroundXanthogranulomatous cholecystitis (XGC) and gallbladder carcinoma (GBC) share similar imaging and serological profiles, posing significant challenges in accurate preoperative diagnosis. This study aimed to identify reliable indica…