Ishihara H

No ORCID on file · 18 papers in corpus · active 2000-2018

Study types

  • article 13
  • other 3
  • review 1

Condition tags

  • endometriosis 16
  • adenomyosis 7
  • dysmenorrhea 1
  • chronic_pelvic_pain 1
article 2018
BMC neurology ·doi:10.1186/s12883-018-1169-2

BACKGROUND: Cerebral infarction associated with a malignant tumor is widely recognized as Trousseau syndrome. In contrast, few cases of cerebral infarction associated with benign tumors have been reported. We present two cases of embolic st…

2016
World journal of gastrointestinal pharmacology and therapeutics ·doi:10.4292/wjgpt.v7.i3.440

AimTo classify changes over time in causes of lower gastrointestinal bleeding (LGIB) and to identify factors associated with changes in the incidence and characteristics of diverticular hemorrhage (DH).MethodsA total of 1803 patients underw…

article 2007
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.2007.00533.x

PROBLEM: Endometriosis is an immune-related chronic inflammatory disease with a polygenic predisposition. The aim of this study was to investigate whether polymorphisms in killer cell immunoglobulin-like receptors (KIRs) is responsible, in …

article 2007
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.05.052

Pelvic pain associated with endometriosis was treated by the long-term administration of a tapering dose of danazol or mid/low doses of oral contraceptives after the end of therapy involving a GnRH agonist (GnRH-a). Results demonstrated tha…

article 2006
Journal of the Society for Gynecologic Investigation ·doi:10.1016/j.jsgi.2006.03.005

ObjectiveThe peroxisome proliferator-activated receptor-gamma (PPAR-gamma) is a nuclear hormone receptor that plays an important role in many diseases. This study investigated whether two polymorphisms (Pro12Ala in exon B and C161T in exon …

article 2006
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.2006.00426.x

PROBLEM: Endometriosis is an immune-related, chronic inflammatory disease with a polygenic predisposition. The aim of this study was to investigate whether the interleukin-6 (IL-6) gene promoter region polymorphism (-634C/G) and the interce…

article 2005
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2004-0871

Allograft inflammatory factor-1 (AIF-1) is a cytokine originally identified in rat cardiac allografts with chronic rejection. AIF-1 is expressed in various human immune-related tissues and is thought to play a role in inflammatory responses…

article 2005
Human Reproduction ·doi:10.1093/humrep/deh890

BACKGROUND: The aim of this study was to evaluate the diagnostic significance of CA-125 for endometriosis without ovarian endometriomas. METHODS: Preoperative serum CA-125 levels were measured in 775 consecutive women diagnosed by laparosco…

article 2003
Fertility and Sterility ·doi:10.1016/s0015-0282(02)04813-6

ObjectiveTo investigate whether GnRH agonists or danazol therapy normalizes estrogen metabolism in the eutopic endometrium of women with endometriosis, adenomyosis, or leiomyomas.DesignProspective clinical study.SettingUniversity hospital.P…

article 2002
Human immunology ·doi:10.1016/s0198-8859(02)00438-x

Although the exact etiology of endometriosis is unclear, several lines of evidence support roles for both cell-mediated and humoral immunity in its pathogenesis. To assess the association between HLA genotypes and endometriosis, we investig…

article 2002
Human Reproduction ·doi:10.1093/humrep/17.4.897

BACKGROUND: To investigate whether polymorphisms of CYP17 and CYP19 genes are associated with the risk of endometriosis, we analysed the frequency and distribution of a single nucleotide polymorphism at the 5' untranslated region of the CYP…

review 2002
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/s0960-0760(02)00260-1

Endometriosis, defined as the presence of endometrial glands and stroma outside of the uterine cavity, develops mostly in women of reproductive age and regresses after menopause or ovariectomy, suggesting that the growth is estrogen-depende…

other 2002
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1034/j.1600-0897.2002.1o029.x

PROBLEM: Interleukin-10 (IL-10) is an important immunomodulatory cytokine. The aim of this study was to investigate whether polymorphisms of the IL-10 gene promoter polymorphisms may be responsible in part for genetic susceptibility to endo…

article 2001
Nihon rinsho. Japanese journal of clinical medicine
article 2001
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/s0301-2115(01)00288-3

An immunohistochemical study was made of a case of serous cystadenocarcinoma that had been shown to have arisen from ovarian endometriosis. Aromatase cytochrome P450 (P450arom), an enzyme responsible for estrogen biosynthesis, was localized…

other 2001
Human Reproduction ·doi:10.1093/humrep/16.1.51

Endometriosis, adenomyosis and leiomyomata develop in women of reproductive age and regress after menopause or ovariectomy, suggesting that they grow in an oestrogen-dependent fashion. We investigated whether polymorphism in the oestrogen r…

other 2000
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.85.5.6567

Leptin is secreted by adipocytes and regulates appetite through interaction with hypothalamic leptin receptors (OB-R). Accumulated evidence shows that leptin is involved in the stimulation of reproductive functions and that local expression…

article 2000
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.85.9.6829

In the human endometrium, inactivation of 17beta-estradiol to estrone is catalyzed by 17beta-hydroxysteroid dehydrogenase type 2 (17betaHSD2). Previous studies have shown that the 17betaHSD2 activity in the endometrium is elevated during th…