Huan Yang

OBJECTIVE: To summarize the clinical features, risk factors, and maternal and fetal outcomes of spontaneous complete uterine rupture during the second and third trimester of pregnancy, and to explore key aspects of early identification and …

OBJECTIVE: To develop and validate a simple yet effective nomogram based on clinical and ultrasound factors for predicting the malignant risk of ovarian-adnexal masses and to evaluate its diagnostic performance and clinical utility. METHOD…

To compare the 12-month clinical outcomes of laparoscopic RFA alone with those of laparoscopic RFA combined with LNG-IUS in patients with symptomatic adenomyosis. This single-center retrospective cohort study included 70 patients with adeno…

BACKGROUND: Inflammation is central to the pathogenesis of endometriosis. High-density lipoprotein (HDL)-related lipid ratios have been proposed as indicators of systemic metabolic inflammation, yet their associations with endometriosis sta…

BACKGROUND: Anti-Müllerian hormone (AMH) is secreted by granulosa cells in preantral follicles and small antral follicles. There is limited information about whether serum AMH levels are related to pregnancy outcomes during in vitro fertili…

The uterine endometrium, which lines the mammalian uterus, is essential for embryo implantation. This lining undergoes significant changes during sexual and menstrual cycles. The endometrium is also associated with hormone-related diseases …

Endometriosis is an inflammatory gynecological disorder characterized by endometrial tissue growth located outside of the uterine cavity in addition to chronic pelvic pain and infertility. In this study, we aim to develop a potential therap…

BACKGROUND: To investigate the characteristics of deep infiltrating endometriosis (DIE) lesion distribution when associated with ovarian endometrioma (OEM). METHODS: The present study analyzed retrospective data obtained by the First Affil…

Abstract Purpose: To investigate the characteristics of deep infiltrating endometriosis (DIE) lesion distribution when associated with ovarian endometrioma (OEM). Methods:The present study analyzed retrospective data obtained by the First A…

Abstract Background: To investigate the characteristics of deep infiltrating endometriosis (DIE) lesion distribution when associated with ovarian endometrioma (OEM). Methods: The present study analyzed retrospective data obtained by the Fir…

Granulosa cells (GCs) are somatic cells surrounding oocytes within follicles and are essential for folliculogenesis. Pathological changes in GCs are found in several ovarian disorders. Recent reports have indicated that long non-coding RNAs…

Endometriosis is characterized by eutopic endometrial cell 'metastasis' to ectopic foci. FOXA2 is a member of the forkhead transcription factor family, which may participate in transcriptional regulation in endometrial cells and contribute …

This study aimed to investigate the effects of estrogen in combination with aspirin and intrauterine balloon on the uterine endometrial repair and reproductive prognosis in patients after surgery for severe intrauterine adhesion (sIUA). We …

Endometriosis is a common gynecological disease found in approximately 10% of reproductive-age women. Gene expression analysis has been performed to explore alterations in gene expression associated with endometriosis; however, the underlyi…

Squamous cell carcinoma antigen (SCCa), as a tumor biomarker, plays an important role in adjuvant diagnosis, treatment evaluation, and prognosis prediction for cervical cancer patients. Localized surface plasmon resonance (LSPR) technique b…

BACKGROUND: Detection of the human epididymis secretory protein 4 (HE4) biomarker plays an important role in the early diagnosis of ovarian cancer. This study aimed to develop a novel localized surface plasmon resonance (LSPR) biosensor for…

FKBP4 (FKBP52) and FKBP5 (FKBP51) are progestin receptor (PR) co-chaperone proteins that enhance and inhibit, respectively, progestin-mediated transcription by PR. Here, we examined FKBP4 and FKBP5 expression in the eutopic endometrium of f…