Aaron K. Styer

Fibroids (leiomyomata) are the most common gynecologic tumor, with a prevalence of 20%–80% in reproductive-aged women and 5%–10% in women with infertility [1]. Although 26%–30% of patients are asymptomatic [2,3], it has been estimated that …

Complex interplay of innate and adaptive immune cells has been implicated in the establishment, maintenance, and progression of endometriosis. Defining the identity, activation state, and functional role of immune cells during lesion establ…

PROBLEM: The anti-inflammatory impact of three polyunsaturated fatty acids (3-PUFA) in endometriosis is incompletely understood. The effect of 3-PUFA on endometriosis-like lesions is evaluated as a potential anti-inflammatory treatment targ…

Several inflammatory cytokines and chemokines have been implicated in the pathogenesis of endometriosis. It has also been argued that polyunsaturated fatty acids (PUFA) may attenuate the inflammatory response in a myriad of human diseases. …

Leptin, a 16-kDa cytokine, has been implicated in several reproductive processes and disorders. Notably, elevated leptin levels in the peritoneal fluid of women with mild endometriosis has been demonstrated, suggesting a role for this cytok…