Bo R. Rueda — Endo Lab

article 2016

Next-generation genomic signature highlights sustained AKT and estrogen receptor signaling as key mediators of resistance following phosphatidylinositol 3-kinase (PI3K) inhibition in patient-derived xenograft models with and without PIK3CA gene mutations

·doi:10.1016/j.ygyno.2016.04.383

article 2016

Overactive mTOR signaling leads to endometrial hyperplasia in aged women and mice

Oncotarget ·doi:10.18632/oncotarget.13919

// Preety Bajwa 1 , Sarah Nielsen 2 , Janine M. Lombard 3,4 , Loui Rassam 2,3 , Pravin Nahar 3,5 , Bo R. Rueda 6 , J. Erby Wilkinson 7 , Richard A. Miller 8 and Pradeep S. Tanwar 1 1 Gynaecology Oncology Group, School of Biomedical Sciences…

article 2014

Dendritic Cells Attenuate the Early Establishment of Endometriosis-Like Lesions in a Murine Model

Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719114525267

Complex interplay of innate and adaptive immune cells has been implicated in the establishment, maintenance, and progression of endometriosis. Defining the identity, activation state, and functional role of immune cells during lesion establ…

article 2014

The Anti‐Inflammatory Impact of Omega‐3 Polyunsaturated Fatty Acids During the Establishment of Endometriosis‐Like Lesions

American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.12276

PROBLEM: The anti-inflammatory impact of three polyunsaturated fatty acids (3-PUFA) in endometriosis is incompletely understood. The effect of 3-PUFA on endometriosis-like lesions is evaluated as a potential anti-inflammatory treatment targ…

article 2013

The impact of dendritic cell depletion on the establishment of endometriosis-like lesions in a murine model

·doi:10.1016/j.fertnstert.2013.07.192

article 2011

Defining the Antagonistic Role of Omega-3 Polyunsaturated Fatty Acid in the Establishment and Early Maintenance of Endometriosis-Like Lesions in a Murine Model.

·doi:10.1093/biolreprod/85.s1.379

Several inflammatory cytokines and chemokines have been implicated in the pathogenesis of endometriosis. It has also been argued that polyunsaturated fatty acids (PUFA) may attenuate the inflammatory response in a myriad of human diseases. …

other 2009

Constitutive activation of Beta-catenin in uterine stroma and smooth muscle leads to the development of mesenchymal tumors in mice

Biology of reproduction ·doi:10.1095/biolreprod.108.075648

Leiomyomas and other mesenchymally derived tumors are the most common neoplasms of the female reproductive tract. Presently, very little is known about the etiology and progression of these tumors, which are the primary indication for hyste…

article 2007

Ablation of Leptin Signaling Disrupts the Establishment, Development, and Maintenance of Endometriosis-Like Lesions in a Murine Model

Endocrinology ·doi:10.1210/en.2007-1225

Leptin, a 16-kDa cytokine, has been implicated in several reproductive processes and disorders. Notably, elevated leptin levels in the peritoneal fluid of women with mild endometriosis has been demonstrated, suggesting a role for this cytok…

article 2005

In Vivo Disruption of Leptin Receptor Function Impairs the Establishment and Viability of Endometriosis-Like Lesions

·doi:10.1016/j.fertnstert.2005.07.1018

article 2004

Endometrial cancer expresses the Mullerian Inhibiting Substance (MIS) type II receptor and is growth inhibited by MIS

·doi:10.1016/j.jamcollsurg.2004.06.001

Renaud, Elizabeth J. MD; Oliva, Esther MD; Rueda, Bo PhD; MacLaughlin, David PhD; Donahoe, Patricia MD Author Information