Craig A. Witz

No ORCID on file · 42 papers in corpus · active 1994-2010

Study types

  • article 31
  • review 6
  • book-chapter 2
  • other 2
  • letter 1

Condition tags

  • endometriosis 16
  • mesh:D004715 14
  • infertility 1
article 2010
Imatinib decreases endometrial stromal cell transmesothial migration and proliferation in the extracellular matrix of modeled peritoneum
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.04.018
book-chapter 2010
Pathogenesis of Endometriosis
·doi:10.4324/9780203319390_chapter_5
article 2009
Peroxisome-proliferator activator receptor-gamma activation decreases attachment of endometrial cells to peritoneal mesothelial cells in an in vitro model of the early endometriotic lesion
Molecular human reproduction ·doi:10.1093/molehr/gap061

The aim of this study was to investigate whether peroxisome proliferator-activated receptor (PPAR)-gamma activation has an effect on the attachment of endometrial cells to peritoneal mesothelial cells in a well-established in vitro model of…

article 2008
Activin A increases invasiveness of endometrial cells in an in vitro model of human peritoneum
·doi:10.1093/molehr/gan016

The aim of this study was to investigate whether activin A has an effect on the attachment and/or invasion of endometrial cells in a modeled peritoneum in vitro. Cultured endometrial stromal cells (ESCs) and endometrial epithelial cells (EE…

article 2008
A potential role for colony-stimulating factor 1 in the genesis of the early endometriotic lesion
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.09.050
article 2008
Imatanib alters expression of endometrial stromal cell signaling genes involved in cell proliferation and metastasis
·doi:10.1016/j.fertnstert.2008.07.244
article 2008
Imatinib decreases the rate of early endometriotic lesion formation in a murine model
·doi:10.1016/j.fertnstert.2008.07.238
article 2008
Modeling the early endometriotic lesion: mesothelium-endometrial cell co-culture increases endometrial invasion and alters mesothelial and endometrial gene transcription
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.09.047
article 2008
Peritoneal mesothelial cell secretory products increase invasion of endometrial stromal cells in an in vitro model of the early endometriotic lesion
·doi:10.1016/j.fertnstert.2008.07.241
article 2007
An in vivo model suggests that colony stimulating factor-1 plays a critical role in the genesis of the early endometriotic lesion
·doi:10.1016/j.fertnstert.2007.07.703
article 2007
Imatinib decreases endometrial stromal cell transmesothelial migration and proliferation in the extracellular matrix of modeled peritoneum
·doi:10.1016/j.fertnstert.2007.07.208
article 2007
IN VITRO MODELS OF ENDOMETRIOSIS
·doi:10.1093/biolreprod/77.s1.71a

There is mounting evidence that retrograde menstruation and implantation of endometrial fragments are the primary factors responsible for development of the majority of endometriotic lesions. Many crucial questions concerning the initial in…

article 2007
Menstrual endometrial cells from women with endometriosis demonstrate increased adherence to peritoneal cells and increased expression of CD44 splice variants
·doi:10.1016/j.fertnstert.2007.07.717
article 2006
O-5
·doi:10.1016/j.fertnstert.2006.07.007
article 2006
P-341
·doi:10.1016/j.fertnstert.2006.07.697
other 2005
A novel in vitro model of the early endometriotic lesion demonstrates that attachment of endometrial cells to mesothelial cells is dependent on the source of endometrial cells
Fertility and sterility ·doi:10.1016/j.fertnstert.2004.10.058

OBJECTIVE: To characterize the source of variability in endometrial stromal cell (ESC) binding to peritoneal mesothelial cells (PMC). DESIGN: In vitro study. SETTING: University medical center. PATIENT(S): Reproductive-age women without …

article 2005
Colony Stimulating Factor-1 Promotes Endometrial Cell Migration and Proliferation in Two and Three-Dimensional Culture
·doi:10.1016/j.fertnstert.2005.07.295
article 2005
Modeling endometriosis
·doi:10.1016/j.fertnstert.2005.03.023
article 2005
Protein Kinase C (PKC)-Dependent Signaling Pathways Promote the Genesis of the Early Endometriotic Lesion
·doi:10.1016/j.fertnstert.2005.07.470
article 2004
Characterization of a novel three-dimensional model of the early endometriotic lesion
·doi:10.1016/j.fertnstert.2004.07.176
book-chapter 2004
Pathogenesis of Endometriosis
·doi:10.3109/9780203319390-12

Endometriosis was described as a disease process over 300 years ago. In the late 17th century it was recognized as peritoneal ‘ulcers’ occurring on the surface of the bladder, intestine, and surface of the uterus.1 In the 18th century physi…

article 2004
Tumor necrosis factor-alpha (TNF-alpha) induces peritoneal mesothelial (PMC), endometrial epithelial (EEC) and endometrial stromal (ESC) cell expression of genes involved in invasion and metastasis
·doi:10.1016/j.fertnstert.2004.07.434
review 2003
Cell Adhesion Molecules and Endometriosis
Seminars in reproductive medicine ·doi:10.1055/s-2003-41324

The pathogenesis of endometriosis remains poorly defined. The interaction of endometrium with peritoneum is an important aspect of the disease process. Cell adhesion molecules (CAMs) are transmembrane receptors that facilitate intercellular…

review 2003
Pathogenesis of endometriosis — Current research
Human fertility (Cambridge, England) ·doi:10.1080/1464770312331368973

Proliferative, secretory and menstrual endometrial cells of both the stroma and epithelium adhere to intact peritoneal mesothelium and mesothelial monolayers. Endometrial attachment to the mesothelium appears to occur rapidly (within 1 h) a…

other 2003
Time series analysis of transmesothelial invasion by endometrial stromal and epithelial cells using three-dimensional confocal microscopy
Fertility and Sterility ·doi:10.1016/s0015-0282(02)04834-3

OBJECTIVE: To evaluate endometrial adhesion and invasion of peritoneal mesothelium. DESIGN: Descriptive study using confocal laser-scanning microscopy. SETTING: University-based laboratory. PATIENT(S): Women undergoing surgery for benign…