Alexander Kopelman

The etiopathology of endometriosis is poorly understood, and retrograde menstruation continues to be the most accepted theory to explain its development. Endometrial stromal cells (eSCs) and endometrial epithelial cells (eECs) have been ext…

Abstract The role of the endometrium in the pathogenesis of endometriosis has assumed prominence. Abnormality of gene and protein expression, apoptosis and changes in cell cycle have been extensively studied in endometriosis. We evaluated t…

Endometriosis is a chronic gynecological disorder defined as the presence of endometrial tissue within extra-uterine sites. The primary symptoms are infertility and chronic pain. The inflammatory environment and aberrant immune responses in…

SUMMARY: The lack of diagnostic markers of endometriosis causes the surgery to be performed for this purpose. It is an invasive method of high cost contributing to the global scenario, where there has been an average of seven years before t…

A falta de marcadores diagnósticos da endometriose faz com que a cirurgia seja realizada com este objetivo. Trata-se de um método invasivo de alto custo colaborando para o cenário mundial, em que observa-se em média sete anos para que a doe…

This literature review analyzed the evidence on nutritional aspects related to the pathogenesis and progression of endometriosis. Diets deficient in nutrients result in changes in lipid metabolism, oxidative stress and promote epigenetic ab…