Craig A. Witz

No ORCID on file · 42 papers in corpus · active 1994-2010

Study types

  • article 31
  • review 6
  • book-chapter 2
  • other 2
  • letter 1

Condition tags

  • endometriosis 19
  • infertility 1
article 2002
An In Vitro Model to Study the Pathogenesis of the Early Endometriosis Lesion
Annals of the New York Academy of Sciences ·doi:10.1111/j.1749-6632.2002.tb02790.x

OBJECTIVE: To determine if whole fragments of endometrium can adhere to peritoneum with intact mesothelium. DESIGN: Tissue culture and immunohistochemical study. SETTING: University Medical Center. PATIENTS: Reproductive-age women undergoin…

article 2002
Culture of menstrual endometrium with peritoneal explants and mesothelial monolayers confirms attachment to intact mesothelial cells
·doi:10.1093/humrep/17.11.2832

BACKGROUND: To evaluate adhesion of menstrual endometrium (ME) to intact peritoneal mesothelium. METHODS: Explants of peritoneum were cultured for 1 h with ME (n = 6). Specimens were serially sectioned for haematoxylin and eosin stain and i…

review 2002
Endometriosis and infertility: is there a cause and effect relationship?
Gynecologic and obstetric investigation ·doi:10.1159/000049418

An association between endometriosis and infertility has long been noted. Endometriosis affects approximately 5% of the general population. In infertile women, the prevalence may be as high as 30%. Multiple studies, the majority of which ar…

article 2002
Menstrual endometrium and individual endometrial stromal and epithelial cells are unique in their ability to adhere to and invade peritoneal mesothelium
·doi:10.1016/s0015-0282(02)04047-5
review 2002
Pathogenesis of Endometriosis
Gynecologic and obstetric investigation ·doi:10.1159/000049425

Various theories have been promulgated to explain the pathogenesis of endometriosis. Interest in the genesis of the endometriotic lesion has been a focus since the earliest investigations. More recently, investigators have addressed aspects…

article 2002
The α2β1 and α3β1 integrins do not mediate attachment of endometrial cells to peritoneal mesothelium
·doi:10.1016/s0015-0282(02)03340-x
article 2001
Attachment of endometrial cells to peritoneum—facilitated? Reply of the authors:
·doi:10.1016/s0015-0282(01)01883-0
article 2001
Reply of the authors:
·doi:10.1016/s0015-0282(01)01995-1
article 2001
Short-term culture of peritoneum explants confirms attachment of endometrium to intact peritoneal mesothelium
Fertility and Sterility ·doi:10.1016/s0015-0282(00)01699-x
article 2000
Expression of the α2β1 and α3β1 integrins at the surface of mesothelial cells: a potential attachment site of endometrial cells
Fertility and Sterility ·doi:10.1016/s0015-0282(00)00701-9
letter 2000
Interleukin-6: another piece of the endometriosis-cytokine puzzle
Fertility and Sterility ·doi:10.1016/s0015-0282(99)00556-7
article 2000
Time Series Analysis of Transmesothelial Invasion by Endometrial Stromal and Epithelial Cells Using Three-Dimensional Confocal Microscopy
·doi:10.1016/s0015-0282(00)00778-0
article 1999
Current Concepts in the Pathogenesis of Endometriosis
Clinical obstetrics and gynecology ·doi:10.1097/00003081-199909000-00013
article 1999
Whole explants of peritoneum and endometrium: a novel model of the early endometriosis lesion
Fertility and Sterility ·doi:10.1016/s0015-0282(98)00400-2
review 1997
Pathogenesis
Seminars in reproductive endocrinology ·doi:10.1055/s-2008-1068749

There are many hypotheses concerning the pathogenesis of endometriosis, though no single theory can explain all cases. It is likely that several mechanisms are involved. Early studies concentrated on the histogenesis of the endometriotic le…

review 1995
Abnormal uterine bleeding
·doi:10.1016/s0025-7125(16)30071-2
article 1994
Characterization of Lymphocyte Subpopulations and T Cell Activation In Endometriosis
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.1994.tb01110.x

PROBLEM: Numerous studies have characterized the lymphocyte subpopulations in normal eutopic endometrium and suggested a role for the cytokine secretory products of these lymphocytes in regulating endometrial cell proliferation and differen…