Ptak A

No ORCID on file · 5 papers in corpus · active 2024-2026
2026
Editorial: Advances on molecular mechanisms regulating reproduction - from gametogenesis to fertilization.
Frontiers in molecular biosciences ·doi:10.3389/fmolb.2026.1850838
2026
Follicular fluid from women with polycystic ovary syndrome induces granulosa cells metabolic dysfunction that is exacerbated by obesity.
Frontiers in endocrinology ·doi:10.3389/fendo.2026.1783780

BackgroundPolycystic ovary syndrome (PCOS) is characterized by altered follicular development and metabolic dysfunction, frequently exacerbated by obesity. The follicular fluid (FF) microenvironment plays a critical role in supporting oocyt…

2025
Energy imbalance in oPOI ovarian granulosa cells is linked to reduced glucose bioavailability and metabolism.
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-025-01426-8

BackgroundPremature ovarian insufficiency (POI), affecting approximately 1% of women under 40, is associated with impaired fertility. Occult POI (oPOI), an initiating form, is more challenging to detect but still allows potential success wi…

2025
The Ovary as a Target Organ for New Generation Bisphenols Toxicity.
Toxics ·doi:10.3390/toxics13030164

Bisphenols (BPs) are a group of organic compounds used extensively in plastics, coatings, and epoxy resins; they have been of concern recently due to their endocrine-disrupting effects. Among these, bisphenol A (BPA) is the most studied. Re…

2024
Myo-Inositol and D-Chiro-Inositol Reduce DHT-Stimulated Changes in the Steroidogenic Activity of Adult Granulosa Cell Tumors.
International journal of molecular sciences ·doi:10.3390/ijms252010974

Considering the properties of myo-inositol (MI) and D-chiro-inositol (DCI), which are well known in polycystic ovary syndrome therapy, and the limitations of adult granulosa cell tumor (AGCT) treatment, especially for androgen-secreting tum…