BACKGROUND: Pulmonary alveolar proteinosis (PAP) is a rare pulmonary disorder characterized by impaired surfactant clearance due to alveolar macrophage dysfunction. Leuprorelin acetate, a gonadotropin-releasing hormone agonist, is widely us…
Introduction: Chronic pelvic pain syndrome is a common condition characterized by persistent symptoms that are difficult to treat. Repetitive transcranial magnetic stimulation (rTMS) is considered a safe treatment option for alleviating chr…
Endometriosis, the most prevalent cause of infertility, is associated with anatomical distortion leading to adhesions and fibrosis, as well as endocrine abnormalities and immune disorders. This review discusses the mechanisms underlying end…
Endometriosis (EM), also known as Zhengjia in traditional Chinese medicine, is a common disease that significantly impacts women's health. An integrated treatment approach combining traditional Chinese medicine (TCM) and western medicine ha…
Abstract This study focused on elucidating the role of PANoptosis in osteosarcoma (OS), a highly malignant bone tumor. By screening and integrating OS-related microarray datasets from GEO, we identified 105 PANoptosis-related differentiall…
Abstract Background Prunus tomentosa Thunb. is a fruit tree native to China and has a wide natural distribution range. The germplasm resources are found in the six geographical regions of China and comprises a variety of ecological types.…
Endometriosis (EMS) is defined as the appearance, growth, infiltration, and repeated bleeding of endometrioid tissue (glands and stroma) outside the uterus cavity, which can form nodules and masses. Endometriosis is a chronic inflammatory e…
Abstract Additive manufacturing technology has rapidly developed to enable the manufacturing of various complex feature parts. However, parts manufactured through Laser Metal Deposition (LMD) often exhibit poor surface quality with the wav…
Endometriosis is a chronic inflammatory disease. The immune-checkpoint molecules CD226 and TIGIT play an important role in regulating T cells' function. However, little is known about the proportion and function of CD226 and TIGIT on CD4+ T…
The immune system contributes to the pathophysiology of endometriosis. The role of ThGM cells, which produce granulocyte macrophage-colony-stimulating factor (GM-CSF), in the pathogenesis of endometriosis remains unknown. To analyze the fea…
Microorganisms are ubiquitous in the human body; they are present in various areas including the gut, mouth, skin, respiratory tract, and reproductive tract. The interaction between the microbiome and reproductive health has become an incre…
PURPOSE: To study the therapeutic effects of uterine artery embolization (UAE) on adenomyosis and to investigate the association between uterine blood supply and artery embolization treatment outcomes. METHODS: Using digital subtraction ang…
【Objective】To investigate the pathology change of endometriosis(EMs) rats which were treated by human chorionic gonadotropin(HCG).【Method】Twenty-four endometriosis rat models were established and were divided into three groups,then were tre…
ObjectiveRecent studies have shown that the local expression of soluble interleukin (IL) -1 receptor type II (sIL-1 RII) in endometrial tissue of women with endometriosis is decreased, and the depression of IL-1 RII was more significant in …
Objective To establish a dynamic endometriosis nude mouse model that allows noninvasive assessment of lesion implantation and development. Methods Twenty-five female nude mice were devided into subcutaneous group(SC,11mice) and intraperiton…
AIM: To develop a gene therapy vector of interleukin-1 receptor II(IL-1RII) with recombinant adenovirus and express IL-1RII in the eutopic stromal cells of endometriosis(EM). METHODS: Get full length of cDNA with IL-1RII gene was obtained b…
ObjectiveTo determine the role of interleukin-1 receptor type II (IL-1RII) in the pathogenesis of endometriosis.DesignCultures of endometrial cells exposed to soluble IL-1RII or the recombinant adenovirus of IL-1RII (rAd-RII).SettingGynecol…
Objective: To explore the effects of soluble interleukin-1 receptor type Ⅱ (sIL-1RⅡ) on interleukin-1α (IL-1α)-induced expression of IL-8 in eutopic endometrial stromal cells (ESC) from patients with endometriosis (EMs). Methods: ESC from p…