Ren L

No ORCID on file · 13 papers in corpus · active 2018-2026

Study types

  • article 7
  • preprint 1

Condition tags

  • endometriosis 7
  • infertility 4
  • dysmenorrhea 1
  • adenomyosis 1
2026
Advanced science (Weinheim, Baden-Wurttemberg, Germany) ·doi:10.1002/advs.202510631

Neurogenic bladder (NB)-induced fibrosis is the major cause of irreversible bladder dysfunction, yet the underlying mechanisms remain undefined. Here, leveraging single-cell RNA sequencing, the fibrotic landscape of NB is delineated and a d…

article 2026
Journal of translational medicine ·doi:10.1186/s12967-025-07648-z

BACKGROUND: Ovarian endometriosis (OEMs) is a primary cause of female infertility and is driven primarily by fibrosis, which disrupts the ovarian follicular microenvironment. Pirfenidone (PFD), an FDA-approved antifibrotic drug, holds promi…

article 2025
Pakistan journal of pharmaceutical sciences

Curcumol (Cur) has been found to be useful in improving Endometriosis (EMS), however its mechanism of action is still not completely understood. Based on this, the current study was carried out to investigate the mechanism of Cur on the inv…

2025
Frontiers in genetics ·doi:10.3389/fgene.2025.1720842

Recurrent spontaneous abortion (RSA), defined as two or more consecutive pregnancy losses, affects 1%-5% of couples and poses a significant challenge to reproductive health. Despite its prevalence, the underlying etiology remains elusive in…

article 2025
BMC women's health ·doi:10.1186/s12905-025-03700-8

BACKGROUND: Adenomyosis is a common gynecological disorder characterized by the invasion of endometrial tissue into the myometrium, resulting in severe dysmenorrhea and menorrhagia. This study aimed to explore the role of SMOC2 (SPARC relat…

2024
Biomedical engineering online ·doi:10.1186/s12938-024-01276-2

BackgroundIron deficiency anemia (IDA) is a common health problem worldwide. The objective of this study was to noninvasively and quantitatively evaluate early changes in left ventricular systolic function in patients with IDA using the lef…

article 2021
Genetic testing and molecular biomarkers ·doi:10.1089/gtmb.2020.0152

Purpose: This study was designed to reveal the molecular differences between granulosa cells (GCs) from patients with endometriosis and normal controls. Methods: RNA sequencing was performed on GCs from patients with EM-related infertility …

2021
Oxidative medicine and cellular longevity ·doi:10.1155/2021/9921839

Acute pancreatitis (AP), an inflammatory disorder of the pancreas, can cause systemic inflammatory responses. Escin Sodium (ES), a natural mixture of triterpene saponins extracted from the dry ripe fruit of Fructus Aesculi or horse chestnut…

article 2020
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2020.04.010

Research questionWhat is the expression pattern of microRNA (miRNA) in exosomes isolated from eutopic endometrial stromal cells (EuESC) of women with endometriosis-associated infertility?DesignSmall RNA sequencing was conducted in exosomes …

2020
Journal of pain research ·doi:10.2147/jpr.s225230

ObjectiveTo compare the prevalence and characteristics of chronic postsurgical pain (CPSP) between laparoscopic hysterectomy (LH) and abdominal hysterectomy (AH) groups 3, 6, and 12 months after surgery, and to assess the impact of pain on …

preprint 2019
·doi:10.21203/rs.2.19312/v1

Abstract Purpose Although tubal factor infertility (TFI) and endometriosis-related infertility all can result in female infertility, the pathogenesis of TFI and endometriosis-related infertility were different. The pathophysiologic mechanis…

article 2019
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719119828115

Endometriosis is an inflammation-dependent gynecologic disorder. Increased cyclooxygenase-2 (COX-2) expression plays an important role in the development and progression of endometriosis. Lipoxin A4 (LXA4) is an endogenous anti-inflammation…

article 2018
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13074

PROBLEM: The role of the long non-coding RNA (lncRNA) actin filament associated protein 1 antisense RNA1 (AFAP1-AS1) in the etiology of endometriosis is unknown. METHOD OF STUDY: Expression of epithelial-mesenchymal transition (EMT) markers…