Andrew Prentice

BACKGROUND: Endometriosis is a common gynaecological condition that frequently presents with the symptom of pain. The precise pathogenesis (mode of development) of endometriosis is unclear but it is evident that endometriosis arises by the …

BACKGROUND: Endometriosis is a common gynaecological condition that frequently presents with the symptom of pain. The precise pathogenesis (mode of development) of endometriosis is unclear but it is evident that endometriosis arises by the …

OBJECTIVE: To determine whether an educational package could influence the management of menorrhagia, increase the appropriateness of choice of non-hormonal treatment, and reduce referral rates from primary to secondary care. DESIGN: Random…

Concerns about high rates of hysterectomy have increased interest in alternative surgical and medical treatments for menorrhagia. Hysteroscopic procedures that ablate and resect the endometrium without hysterectomy have been widely adopted …

Reproductive Molecular Research Group, Department of Obstetrics and Gynaecology, University of Cambridge, Clinical School, The Rosie Maternity Hospital, Cambridge, United Kingdom. Hum Reprod 1996;11:220-223

(1995). Gynaecological case reports: Successful medical treatment of sub-diaphragmatic endometriosis. Journal of Obstetrics and Gynaecology: Vol. 15, No. 3, pp. 206-206.

OBJECTIVE: To compare the expression of cell adhesion molecules by endometrium and endometriosis. DESIGN: A comparative study of integrin expression, determined immunohistochemically, in eutopic and ectopic endometrium biopsied synchronousl…

proportions of abnormal findings.Although many negative results will be clinically useful, an unduly high negative percentage would suggest that the referral threshold needed to be reviewed.

Growth factors play a role in the cyclical growth and vascularization of normal endometrium. Abnormal endometrial proliferation and neovascularization may result in endometriosis. This study determines the presence and localization of acidi…

OBJECTIVE: To study epidermal growth factor (EGF) receptor expression in endometrium throughout the menstrual cycle and to compare EGF-receptor expression in endometrium from patients with endometriosis with receptor expression in synchrono…

Endometriosis is an oestrogen dependent condition and it is expected that the tissue of origin of endometriosis will express receptors for the ovarian steroids. Two epithelia, endometrium and peritoneal mesothelium, are the potential parent…

It is 130 years since the first description of endometriosis and yet this enigmatic disease still continues to confound gynaecologists. In the last five years there has been evidence which suggests that endometriosis is a much more common f…

Endometrial proliferation is stimulated by oestradiol. The precise mechanism is poorly understood, but may be mediated by epidermal growth factor (EGF). The aim of the present study was to assess the effects of oestradiol and EGF on glandul…