When treating chronic pelvic pain in women, consider peripheral and central contributors

In: Drugs & Therapy Perspectives · 2017 · vol. 33(9) , pp. 418–423 · doi:10.1007/s40267-017-0429-3 · W2746366543
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AI-generated summary by claude@2026-06+body, 2026-06-13

Chronic pelvic pain in women often arises from both peripheral and central sources and requires pharmacological and non-pharmacological treatments.

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This adapted review discusses chronic pelvic pain in women as a multimodal condition with contributions from both peripheral sources and central neurobiological and neuropsychological factors, and it outlines pharmacological and non-pharmacological management options at a high level. It summarizes medication classes including analgesics, hormonal suppression, anesthetics, antidepressants, membrane stabilizers, and anxiolytics, alongside interventions such as pelvic floor physical therapy, cognitive behavioural therapy, and lifestyle modifications. The main caveat is that it is a narrative review/adaptation rather than new primary research, and the excerpt does not provide detailed evidence weighting for each specific treatment. Relevance to endometriosis: it cites multiple endometriosis-focused therapies and evidence (e.g., clinical management of endometriosis and reviews/trials of gonadotropin-releasing hormone analogues and other hormonal agents), though its main focus is a broad framework for chronic pelvic pain including peripheral and central mechanisms.

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Abstract

The management of chronic pelvic pain (CPP) in women requires a multimodal approach, as such pain is often generated both centrally and peripherally. The role of neurobiological and neuropsychological factors in contributing to CPP should be considered. The comprehensive management of CPP in women includes the use of pharmacological options (e.g. analgesics, hormonal suppression, anaesthetics, antidepressants, membrane stabilizers and anxiolytics) and non-pharmacological interventions (pelvic floor physical therapy, cognitive behavioural therapy, lifestyle modifications). Similar content being viewed by others

References

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Drugs Ther Perspect 33, 418–423 (2017). https://doi.org/10.1007/s40267-017-0429-3 Published: Issue date: DOI: https://doi.org/10.1007/s40267-017-0429-3

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