Invasive Diagnostik der Endometriose und Adenomyose

In: Der Gynäkologe · 2010 · vol. 43(11) , pp. 910–917 · doi:10.1007/s00129-010-2588-3 · W1489023395
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Diagnostic laparoscopy is crucial for the complex, chronic disease of endometriosis, with classification systems aiding in comprehensive characterization and future insights potentially from lymph node biopsy and autofluorescence.

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The paper addresses diagnostic approaches for endometriosis with an emphasis on invasive assessment, stating that accurate diagnosis must reflect endometriosis as a complex systemic chronic disease. It highlights diagnostic laparoscopy as central, and describes how disease severity and extent can be characterized using classification systems that capture lesion locations within and outside the peritoneal cavity as well as activity. The authors suggest that future improvements in prognostic and treatment planning could come from sentinel lymph node biopsy, precise histopathological grading of endometriotic lesions, and autofluorescence methods, with the key limitation being that these added techniques are framed as potential future contributions rather than validated in the presented work. This paper is centrally about endometriosis — it focuses on invasive diagnostics including laparoscopy, classification, sentinel lymph node biopsy, histopathology, and autofluorescence for endometriosis (and also mentions adenomyosis in the title).

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Zusammenfassung Endometriose ist eine komplexe systemische und chronische Erkrankung. Die Diagnostik muss diesem Charakter Rechnung tragen. Von entscheidender Bedeutung ist die diagnostische Laparoskopie. Schwere und das Ausmaß der Erkrankung werden über Klassifikationen erfasst, die dazu beitragen, Lokalisationen innerhalb und außerhalb der Peritonealhöhle sowie die Aktivität zu erfassen. Eine Sentinel-Lymphknoten-Biopsie, die Anwendung der Autofluoreszenz sowie eine präzise histopathologische Begutachtung endometriotischer Läsionen könnten zukünftig für Prognose und Therapieplanung von zusätzlicher Bedeutung sein. Abstract Endometriosis is a complex systemic and chronic disease. Precise diagnosis is of utmost importance. Reliable classification systems are available and useful for a comprehensive characterization of the disease. Additional informations concerning prognosis and possible therapeutic strategies may be provided in future by sentinel lymph node biopsy, histopathological grading and using the method of autofluorescence. Similar content being viewed by others Literatur (o A) (1996) ASRM classification of endometriosis. Fertil Steril 67:817–821 Balasch J, Creus M, Fabregues et al (1996) Visible and non-visible endometriosis at laparoscopy in fertile and infertile women and in patients with chronic pelvic pain: a prospective study. Hum Reprod 11:387–391 Brosens I, Puttemans P, Campo R et al (2004) Diagnosis of endometriosis: pelvic endoscopy and imaging techniques. Best Pract Res Clin Obstet Gynaecol 18:285–303 Buchweitz O, Staebler A, Tio J et al (2006) Detection of peritoneal endometriotic lesions by autofluorescence laparoscopy. Am J Obstet Gynecol 195:949–954 Brinton LA, Gridley G, Persson I et al (1997) Cancer risk after a hospital discharge diagnosis of endometriosis. Am J Obstet Gynecol 176:572–579 Demco L (2004) Laparoscopic spectral analysis of endometriosis. J Am Assoc Gynecol Laparosc 11:219–222 D’Hooghe TM (2003) Invisible microscopic endometriosis: how wrong is the Sampson hypothesis of retrograde menstruation to explain the pathogenesis of endometriosis? Gynecol Obstet Invest 55:61–62 Dinulescu DM, Ince TA, Quade BJ et al (2005) Role of K-Ras and Pten in the development of mouse models of endometriosis and endometriod ovarian cancer. Nat Med 11:63–70 Evers JL, Dunselman GA, Groothuis P (2005) Now you see them, now you don’t. Fertil Steril 84:31–32; discussion 38–9. Review Hillemanns P, Weingandt H, Stepp H et al (2000) Assessment of 5-aminolevulinic acid-induced porphyrin fluorescence in patients with peritoneal endometriosis. Am J Obstet Gynecol 183:52–57 Huffman JW (1981) Endometriosis in young teen-age girls. Pediatr Ann 10:44–49 Kang SB, Chung HH, Lee HP et al (2007) Impact of diagnostic laparoscopy on the management of chronic pelvic pain. Surg Endosc 21(6):916–919 Kyama CM, Debrock S, Mwenda JM et al (2003) Potential involvement of the immune system in the development of endometriosis. Reprod Biol Endocrinol 1:121 Kupker W, Linde H van der, Loning M et al (2004) Laparoscopic autofluorescence imaging of endometriosis. Fertil Steril 82:S72–S73 Malik E, Berg C, Meyhofer-Malik A et al (2000) Fluorescence diagnosis of endometriosis using 5-aminolevulinic acid. Surg Endosc 14:452–455 Medina MG, Lebovic DI (2009) Endometriosis – associated nerve fibers and pain. Acta Obstet Gynecol Scand 88:968–975 Melin A, Sparen P, Persson I (2006) Endometriosis and the risk of cancer with special emphasis on ovarian cancer. Hum Reprod 21:1237–1242 Murphy AA, Green WR, Bobbie D et al (1986) Unsuspected endometriosis documented by scanning electronmicroscopy in visualy normal peritoneum. Fertil Steril 46:522–524 Pellicer A, Albert C, Garrido N et al (2000) The pathophysiology of endometriosis – associated infertility: follicular environment and embryo quality. J Reprod Fertil Suppl 55:109–119 Redwine DB (1999) Ovarian endometriosis: a marker for more extensive pelvic and intestinal disease. Fertil Steril 72:310–315 Sampson JA (1925) Endometrial carcinoma of ovary arising in endometrial tissue in that organ. Arch Surg 10:1–72 Sinaii N, Ceary SD, Ballweg ML (2002) High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis. Hum Reprod 17:2715–2724 Tuttlies F, Keckstein J, Ulrich U et al (2005) ENZIAN score: a classification of deep infiltrating endometriosis. Zentralbl Gynakol 127:275–281 Wolfram F, Riedlinger J, Weichbrodt M et al (2010) Sentinel lymph node labeling of patients with deep infiltrating rectovaginal endometriosis – does this make sense? J Endometriosis 2:33–40 Interessenkonflikt Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Küpker, W., Knoll, M. Invasive Diagnostik der Endometriose und Adenomyose. Gynäkologe 43, 910–917 (2010). https://doi.org/10.1007/s00129-010-2588-3 Published: Issue date: DOI: https://doi.org/10.1007/s00129-010-2588-3 Schlüsselwörter - Diagnostische Laparoskopie - Autofluoreszenz - Sentinel-Lymphknoten-Biopsie - Maligne Transformation - Fertilität - Unterbauchschmerzen

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