Management of Recurrent Endometriosis After Hysterectomy and Bilateral Salpingo-Oophorectomy

In: Endometriosis · 1995 · pp. 189–192 · doi:10.1007/978-1-4613-8404-5_18 · W1872177572
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Recurrent endometriosis after hysterectomy and bilateral salpingo-oophorectomy is considered rare, with historical data suggesting a link between hormone replacement therapy and recurrence rates.

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This chapter reviews the reported incidence and management considerations for persistent or recurrent endometriosis after total abdominal hysterectomy with bilateral salpingo-oophorectomy (TAH BSO), highlighting the concept that cyclic ovarian steroid exposure can stimulate endometrial implants and that its removal should allow regression. It summarizes older reports with small numbers suggesting recurrence is extremely rare after TAH BSO, with historical series reporting higher recurrence rates when estrogen replacement was given compared with none. A key caveat explicitly noted is that the exact incidence after “definitive” surgery is unknown and prior data derive largely from small reviews and earlier investigations. This paper is centrally about endometriosis — specifically recurrent/persistent endometriosis after hysterectomy and bilateral salpingo-oophorectomy and the role of post-surgical hormone replacement.

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Abstract

Persistent or recurrent endometriosis after a total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH BSO) has been reported by several investigators.1–3 Although many aspects of endometriosis are incompletely understood, the stimulation and growth of endometrial implants by cyclic ovarian steroids has been demonstrated. Therefore, removing this cyclic stimulation should permit the disease to regress. We don’t know the exact incidence of recurrent endometriosis after “definitive” surgery, but it is thought to be extremely rare following TAH BSO even when the woman takes hormone replacement therapy.4 Several investigators have published reviews with small patient numbers. In 1970, Ranney reported no recurrences when estrogen replacement was not given but a 3% recurrence rate if replacement was given.5 In the same decade, Gray reported no recurrence without hormonal replacement therapy compared with a 20% rate if estrogen therapy was initiated.6 Preview Unable to display preview. Download preview PDF. Similar content being viewed by others

References

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