Clinicopathological Analysis of Hysterectomy Specimens

In: Tropical Journal of Pathology and Microbiology · 2019 · vol. 5(5) , pp. 275–280 · doi:10.17511/jopm.2019.i05.04 · W3016965946
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AI-generated summary by claude@2026-06, 2026-06-08

This retrospective analysis of 78 hysterectomy specimens found leiomyoma to be the most common pathology, followed by adenomyosis, with chronic cervicitis often an incidental finding.

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This 6-month retrospective clinicopathological study analyzed 78 hysterectomy specimens at a pathology department by collecting clinical presentation data from inpatient files and corresponding histopathology reports to characterize lesion patterns and their clinico-pathological correlations. The peak age group was 35–45 years (42.30%), with fibroids the most common clinical presentation (42.30%), while leiomyoma was the most common histopathological diagnosis (47.4%). Adenomyosis was identified in 16 cases (12.82%), including 14 cases (10.26%) with dual pathology of leiomyoma and adenomyosis, and chronic cervicitis was noted as the most common incidental histopathological finding. The paper notes that some lesions, including chronic cervicitis and adenomyosis, were encountered as pure incidental findings despite normal gross appearance. This paper is centrally about adenomyosis — it reports the frequency of adenomyosis in hysterectomy specimens and highlights it as an incidental histopathological finding in uterine pathology.

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Abstract

Introduction: The uterus is vital reproductive organ prone to develop several non-neoplastic and neoplastic lesions in womancontributing significantly to increased morbidity and mortality. Although many treatment options are available, hysterectomy isstill widely used treatment modality worldwide. Objectives: The study was proposed to analyse the patterns of lesions in hysterectomy specimens and to analyse the clinico-pathological correlation in hysterectomy specimen. Methods: A 6-monthretrospective study was performed in Department of Pathology, Karwar institute of Medicalscience, Karwar. Baseline data were collected from inpatient files and histopathology reports were collected from Department of Pathology,to identify the most common pathologies in hysterectomy specimens. Results:78 hysterectomy cases were analysed and the peak age group were from 35-45 years (42.30%), and the most common clinical presentation was fibroids (42.30%). Most common histopathological lesion was leiomyoma 37 cases (47.4%), followed by 16 cases (12.82%) presented as adenomyosis, and 14 cases (10.26%) had dual pathology of both leiomyoma and adenomyosis. The commonest incidental histopathological finding seen in hysterectomy specimens was chronic cervicitis. Conclusions: Hysterectomy is the most commonly performed elective major gynaecological surgery. Though the histopathological analysis correlates well with the clinical diagnoses, quite a few lesions like chronic cervicitis and adenomyosis were encountered as pure incidental findings. Hence, it is mandatory that every hysterectomy specimen, even if it grossly appears to be normal, should be subjected to detailed histopathological examination for confirming diagnosis and better postoperative management
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Introduction

The uterus is vital reproductive organ prone to develop several non-neoplastic and neoplastic lesions in womancontributing significantly to increased morbidity and mortality. Although many treatment options are available, hysterectomy isstill widely used treatment modality worldwide.

Objectives

The study was proposed to analyse the patterns of lesions in hysterectomy specimens and to analyse the clinico-pathological correlation in hysterectomy specimen.

Methods

A 6-monthretrospective study was performed in Department of Pathology, Karwar institute of Medicalscience, Karwar. Baseline data were collected from inpatient files and histopathology reports were collected from Department of Pathology,to identify the most common pathologies in hysterectomy specimens. Results:78 hysterectomy cases were analysed and the peak age group were from 35-45 years (42.30%), and the most common clinical presentation was fibroids (42.30%). Most common histopathological lesion was leiomyoma 37 cases (47.4%), followed by 16 cases (12.82%) presented as adenomyosis, and 14 cases (10.26%) had dual pathology of both leiomyoma and adenomyosis. The commonest incidental histopathological finding seen in hysterectomy specimens was chronic cervicitis.

Conclusions

Hysterectomy is the most commonly performed elective major gynaecological surgery. Though the histopathological analysis correlates well with the clinical diagnoses, quite a few lesions like chronic cervicitis and adenomyosis were encountered as pure incidental findings. Hence, it is mandatory that every hysterectomy specimen, even if it grossly appears to be normal, should be subjected to detailed histopathological examination for confirming diagnosis and better postoperative management Downloads

References

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