Cutaneous endometriosis
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This case report details the diagnosis and treatment of a 41-year-old woman with a painful umbilical nodule, ultimately identified as cutaneous endometriosis.
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Abstract
Cutaneous endometriosis is a disorder that primarily affects women of reproductive age. The disorder is most commonly associated with cyclical pain during menses, but it can be difficult to diagnose in the absence of these symptoms and requires biopsy testing for a definitive diagnosis. We report on a case of a 41-year-old patient undergoing hormonal therapy for infertility who presented with a painful firm subcutaneous nodule in the umbilicus. She was ultimately diagnosed with cutaneous endometriosis and underwent surgical excision. In this report, we discuss the differential diagnosis and comment on treatment options, including surgical excision with wide margins or treatment with hormonal agents, such as danazol or leuprolide. Finally, we discuss whether patients with cutaneous endometriosis should receive an additional evaluation for pelvic endometriosis.
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References (6)
- Cutaneous and Subcutaneous Endometriosis via openalex
- Cutaneous endometriosis: Presentation of 33 cases and literature review via openalex
- Postmenopausal Cutaneous Endometriosis: Mimicking Breast Metastasis via openalex
- Primary Cutaneous Endometriosis of Umbilicus via openalex
- Villar’s nodule: A case report and systematic literature review of endometriosis externa of the umbilicus via openalex
- W2029089084 via openalex
Cited by (31)
- Umbilical endometriosis: A case series on the different approaches in management 2025
- Fine-needle Aspiration Cytology of Cutaneous Endometriosis: A Series of 17 Cases with Literature Review 2025
- Do Interventions on the Uterine Wall Increase the Risk of Developing Abdominal Wall Endometrioma? 2025
- Endometriosis in Patients Undergoing Plastic Surgical Procedures: A Case Report and Review of the Literature 2024
- Cutaneous Deciduosis: A Rare Cutaneous Lesion Mimicking Malignancy 2024
- A multilobulated nodule of a cesarean section scar: Think of cutaneous endometriosis 2024
- Cutaneous Endometriosis: a rare medical entity 2023
- A Painful Periumbilical Nodule in a Reproductive-aged Woman 2023
- Is dienogest a convenient treatment option for cesarean scar endometriosis or should it be treated surgically? 2023
- A Classical Case of Cesarean Scar Endometriosis in a 35-Year-Old Woman Presenting with Cyclical Abdominal Pain: A Case Report 2023
- Magnetic Resonance Roadmap in Detecting and Staging Endometriosis: Usual and Unusual Localizations 2023
- Primary versus secondary cutaneous endometriosis: Literature review and case study 2023
- Atypical Sites of Endometriosis: Primary Inguinal Cutaneous Endometriosis 2023
- Endometriosis cutánea espontánea 2023
- Cutaneous endometriosis presented in a 43-year-old woman’s caesarian scar 2022
- Spontaneous Umbilical Endometriosis: A Case Report 2022
- A multilobulated asymptomatic umbilical nodule revealing endometriosis 2021
- Ultrasound Imaging of Abdominal Wall Endometriosis: A Pictorial Review 2021
- Cutaneous Endometriosis: A Case Report 2021
- Painless umbilical nodule in a nulliparous female – A clinical quandary 2021
- Primary inguinal subcutaneous endometriosis accompanied with an inguinal hernia 2021
- Spontaneous cutaneous endometriosis in Mons Pubis: review of literature 2021
- Primary Cutaneous Endometriosis Presenting as an Umbilical Nodule 2021
- Cutaneous Endometriosis: A Case Report and Review of the Literature 2021
- Diagnosis and Treatment of Vulvo-Perineal Endometriosis: A Systematic Review 2021
- Skin endometriosis: A case report and review of the literature 2021
- Female with intermittently bleeding abdominal wall mass 2021
- Endometriosis: A Comprehensive Review 2020
- Spontaneous Cutaneous Endometriosis of the Umbilicus: A Case Report 2017
- Cutaneous endometriosis 2016
- Scar Endometriosis 2016
Source provenance
- europepmc
- last seen: 2026-06-04T01:30:01.192114+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-05-13T22:22:17.025735+00:00
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