Danazol versus carbon dioxide laser plus postoperative danazol: Treatment of infertility due to mild pelvic endometriosis

A P Chong, Augusto P. Chong
Lasers in surgery and medicine · 1985 · vol. 5(6) , pp. 571–576 · doi:10.1002/lsm.1900050605 · PMID:3937007 · W1986851035
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This retrospective study compared danazol alone versus CO2 laser surgery followed by danazol for mild pelvic endometriosis, finding the combined approach yielded better pregnancy rates despite modest sample sizes.

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Abstract

The mechanism of action by which mild pelvic endometriosis causes infertility is still unknown. Danazol has been proposed as the sole agent to treat this condition; however, the results for pregnancy rates do not give as much cause for enthusiasm at the present time as they did when this drug was introduced. To ascertain the role of laser via the laparoscopic approach, this retrospective study looks at the pregnancy success rate in two groups of patients. Group I was treated with danazol alone; group II was treated with danazol after laser surgery. Although the success rate is better in group II, the population sample in both groups is modest and does not allow one to draw meaningful statistical conclusions at the present time, but the use of carbon dioxide laser with the laparoscope plus postoperative danazol seems to be a better approach to this condition that affects the infertile female.

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Condition tags

endometriosisinfertility

MeSH descriptors

Danazol Endometriosis Infertility, Female Laser Therapy Pelvic Neoplasms Pregnadienes Adult Carbon Dioxide Combined Modality Therapy Danazol Endometriosis Female Follow-Up Studies Humans Infertility, Female Infertility, Female Pelvic Neoplasms Postoperative Care Pregnadienes Pregnancy

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (18)

Cited by (5)

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