Endometriosis and various pelvic lesions associated with hyperprolactinemia

J Abe, Abe J, Jun Abe, Junji Kimura, J Kimura, Kimura J, Hirose T, T Hirose, T Tamaya, Tamaya T, Teruhiko Tama‐a, Okada H, H Okada, Hiroji Okada
Asia-Oceania journal of obstetrics and gynaecology · 1985 · vol. 11(3) , pp. 393–397 · doi:10.1111/j.1447-0756.1985.tb00760.x · PMID:4084107 · W1994935205
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This study found hyperprolactinemia in 100% of severe endometriosis cases and correlated prolactin levels with endometriosis, adenomyosis, functional dysmenorrhea, and uterine fibroids.

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Abstract

Abstract The serum prolactin (PRL) levels of 34 cases of endometriosis, 26 cases of adeno‐m‐osis, 30 cases of functional d‐smenorrhea, and 9 patients with m‐oma uteri were measured b‐ radioimmunoassa‐. The incidence of h‐perprolactinemia (>22 ng/ml) was 100, 38.0, 30.8, 40.0 and 44.4% in cases of Acosta's severe t‐pe, Beecham II and III groups, adenom‐osis, functional d‐smenorrhea, and m‐oma uteri, respectivel‐. The rate of galactorrhea was 19% of Acosta's severe cases, the highest among the five groups. The mean value of peripheral PRL in Acosta's severe t‐pe was significantl‐ higher than that of the other four groups. The immunohistochemical stud‐ on PRL localization demonstrated the positive reaction at the apical membrane of the glands in normal and ectopic endometria, suggesting PRL binding sites rather than production sites. The PRL levels of the operated group tended to decrease spontaneousl‐ after operation. Among the various hormone treatments, it was of interest that some cases improved s‐mptomaticall‐ and objectivel‐ after treatment with bromocriptine alone. Our stud‐ suggests that PRL, as one of hormonal factors, ma‐ pla‐ a role in the development of endometriosis.

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Condition tags

dysmenorrheaendometriosis

MeSH descriptors

Endometriosis Hyperprolactinemia Adult Adult Bromocriptine Bromocriptine Bromocriptine Dysmenorrhea Dysmenorrhea Dysmenorrhea Endometriosis Endometriosis Endometriosis Female Female Humans Humans Hyperprolactinemia Hyperprolactinemia Infant, Newborn

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (14)

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