The potential danger of COX-2 inhibitors

Robert J. Norman, Ruijin Wu
Fertility and sterility · 2004 · vol. 81(3) , pp. 493–494 · doi:10.1016/j.fertnstert.2003.10.016 · PMID:15037388 · W2007077370
Other OA: bronze CC0 ⤵ 10 in-corpus citations
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-11 ⓘ

This paper reports on the potential dangers associated with COX-2 inhibitors.

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Abstract

Cyclooxygenase (COX)-2 inhibitors have a major effect on ovulation and may impair fertilization, decidualization, implantation, and parturition, as well as female fertility. Women attempting to become pregnant need to pay more attention to their use of COX-2 inhibitors.

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MeSH descriptors

Cyclooxygenase Inhibitors Isoenzymes Animals Cyclooxygenase 2 Cyclooxygenase 2 Inhibitors Cyclooxygenase Inhibitors Female Humans Isoenzymes Membrane Proteins Ovulation Ovulation Prostaglandin Antagonists Prostaglandin Antagonists Prostaglandin-Endoperoxide Synthases

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