Detection and differential diagnosis of suspected malignant transformation of an endometrioma during pregnancy

Chaudhry S, Shivani Chaudhry, Glanc P, Phyllis Glanc, Salem S, Shia Salem
BMJ case reports · 2013 · vol. 2013 , pp. bcr2012007744 · doi:10.1136/bcr-2012-007744 · PMID:23917357 · PMC3762441 · W2021017228
Case report OA: bronze CC0 ⤵ 2 in-corpus citations
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This case report details the prenatal ultrasound and MRI findings that led to the diagnosis of clear cell carcinoma within a decidualized endometrioma in a pregnant patient.

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Abstract

Asymptomatic female in her early 30s presented for her singleton nuchal translucency ultrasound at 12.4 weeks of gestational age. No fetal abnormalities were seen. A large maternal left adnexal mass was identified, prompting a transvaginal ultrasound. The findings were felt to be consistent with an endometrioma, albeit with a 1 cm solid nodule. At this point, the diagnosis was considered to likely represent a decidualised endometrioma; however, warranting careful follow-up. The 20-week anatomy scan demonstrated an enlarging solid nodule that now contained vascularity within the left adnexal mass prompting an MRI. These features were more suggestive of malignancy, although a decidualised endometrioma, which can demonstrate intrapartum growth and vascularity, remained in the differential. Intrapartum sonographic surveillance documented progressive growth. The lesion was uneventfully removed at the time of delivery. Pathology showed clear cell carcinoma within an endometrioma.

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Condition tags

endometriosisendometrioma

MeSH descriptors

Adnexal Diseases Endometriosis Ovarian Neoplasms Pregnancy Complications, Neoplastic Adnexal Diseases Adnexal Diseases Adult Adult Cell Transformation, Neoplastic Cell Transformation, Neoplastic Diagnosis, Differential Diagnosis, Differential Endometriosis Endometriosis Female Female Humans Humans Ovarian Neoplasms Ovarian Neoplasms

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (16)

Cited by (2)

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License: CC0 · commercial use OK