Unusual Case of Postmenopausal Diffuse Endometriosis Mimicking Metastastic Ovarian Malignancy
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This case report describes diffuse peritoneal endometriosis and ovarian endometriomas in a postmenopausal woman mimicking metastatic ovarian cancer on FDG PET/CT.
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Abstract
Endometriosis is a common gynecologic condition of the premenopausal years. However, postmenopausal endometriosis is rare (2.2%) and thought to be related to high level of circulating estrogen, especially in hormonal replacement therapy. We present a case of a 69-year-old postmenopausal woman, previously healthy and on no regular medication, with diffuse peritoneal endometriosis and bilateral ovarian endometrioma mimicking metastatic ovarian carcinoma on FDG PET/CT. Both ovarian endometrioma had low-grade activity, but more strikingly, there was diffuse FDG-avid peritoneal dissemination and gross ascites. Endometriosis should not be totally disregarded as a differential diagnosis even at postmenopausal status.
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References (9)
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Cited by (12)
- Gastric ectopic pancreatic ductal adenocarcinoma coexisted with endometriosis mimick advanced disease: a case report and literature review 2025
- Assessment of Al18F-NOTA-FAPI-04 PET/CT imaging for visualization and localization of ovarian and peritoneal endometriotic lesions in a rat model 2025
- Clinical Management of Endometriosis in Menopause: A Narrative Review 2024
- Age‐dependent phenotypes of ovarian endometriomas 2022
- A evolução clínica de um caso de endometriose profunda na pós-menopausa 2022
- Interference of Known or Suspected Endometriosis in Reporting FDG PET/CT Performed in Another Indication 2022
- Symptomatic endometriosis developing several years after menopause in the absence of increased circulating estrogen concentrations: a systematic review and seven case reports 2019
- Postmenopausal endometriosis, where are we now? 2019
- Endométriose 2019
- Endometriosis resembling endometrial cancer in a postmenopausal patient 2017
- Ovarian Hyperstimulation and Oocyte Harvesting Prior to Systemic Chemotherapy—A Possible Pitfall in 18F-FDG PET/CT Staging of Oncologic Patients 2016
- Endometriosis Mimicking an Advanced Malignant Tumor 2016
Source provenance
- europepmc
- last seen: 2026-09-21T06:08:07.822426+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:17:39.907309+00:00
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