Treatment of Endometriosis and Chronic Pelvic Pain with Letrozole and Norethindrone Acetate

Chawla S; S Chawla; Sonia Chawla

doi:10.1016/s0377-1237(10)80039-5

Treatment of Endometriosis and Chronic Pelvic Pain with Letrozole and Norethindrone Acetate

Chawla S, S Chawla, Sonia Chawla

Medical journal, Armed Forces India · 2010 · vol. 66(3) , pp. 213–215 · doi:10.1016/s0377-1237(10)80039-5 · PMID:27408303 · PMC4921342 · W2033397457

Non-randomised trial OA: bronze CC0 ⤵ 7 in-corpus citations

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This study investigated the efficacy of letrozole combined with norethindrone acetate in treating endometriosis and chronic pelvic pain.

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Abstract

BACKGROUND: Endometriosis is encountered in 7-10% of actively menstruating women, with a suspected prevalence as high as 22% in asymptomatic women. It is an important cause of chronic pelvic pain. The aim of this study was to evaluate the efficacy and safety of letrozole in combination with norethindrone acetate and calcium in the management of endometriosis associated pelvic pain. METHODS: Prospective non-randomized open label study was carried out including 20 patients with endometriosis related pelvic pain that was refractory to previous treatments. RESULT: In all 14 patients completed the study. All patients showed significant improvement of pain scores and revealed significant improvement of features of endometriosis on being given letrozole in combination with norethindrone acetate and calcium. CONCLUSION: Letrozole is an effective drug for treatment of endometriosis.

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Condition tags

endometriosischronic_pelvic_pain

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (13)

Cited by (8)

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[13] W2412063026 via openalex