Relief of asthma in two patients receiving danazol for endometriosis

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Danazol treatment for endometriosis led to asthma remission in two patients, possibly due to effects on endometriotic tissue or protease inhibitors.

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Abstract

This paper describes two patients with endometriosis in whom treatment with danazol resulted in a concomitant remission of asthma. Neither patient reported an association of clinical symptoms with phases of their menstrual cycle. Whether the remission was fortuitous or related to suppression of the activity of the endometriotic tissue or to the ability of danazol to increase the serum levels of two protease inhibitors that are deficient in patients with asthma remains to be determined.

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Condition tags

endometriosis

MeSH descriptors

Asthma Danazol Endometriosis Pregnadienes Adult Adult Asthma Asthma Asthma Danazol Danazol Danazol Endometriosis Endometriosis Female Female Humans Humans Pregnadienes Pregnadienes

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (7)

Cited by (5)

Source provenance

europepmc
last seen: 2026-10-18T09:30:06.152893+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:58:15.129929+00:00
License: CC0 · commercial use OK