Relief of asthma in two patients receiving danazol for endometriosis.
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Danazol treatment for endometriosis led to asthma remission in two patients, possibly due to effects on endometriotic tissue or protease inhibitors.
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Abstract
This paper describes two patients with endometriosis in whom treatment with danazol resulted in a concomitant remission of asthma. Neither patient reported an association of clinical symptoms with phases of their menstrual cycle. Whether the remission was fortuitous or related to suppression of the activity of the endometriotic tissue or to the ability of danazol to increase the serum levels of two protease inhibitors that are deficient in patients with asthma remains to be determined.
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References (7)
- Cul-de-sac fluid in women with endometriosis: fluid volume and prostanoid concentration during the proliferative phase of the cycle—days 8 to 12 via openalex
- Danazol-Induced Elevation of Serum Alpha1-Antitrypsin in Individuals with Severe Deficiency of this Antiprotease via openalex
- Prostaglandin F in human endometriotic tissue via openalex
- W2414547508 via openalex
- W2091965956 via openalex
- W1974027344 via openalex
- W2210149071 via openalex
Cited by (5)
- Common comorbid disorders in endometriosis patients 2021
- Genetic overlap analysis of endometriosis and asthma identifies shared loci implicating sex hormones and thyroid signalling pathways 2021
- Should Supplemental Estrogen be Used as Steroid-Sparing Agents in Women With Asthma? 1995
- The treatment of glucocorticosteroid-dependent chronic urticaria with stanozolol 1988
- Relief of asthma with danazol. 1985
Source provenance
- europepmc
- last seen: 2026-06-13T06:22:48.782012+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:09:50.790931+00:00
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