The GIFT experience: an evaluation of the outcome of 115 cases

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AI-generated summary by claude@2026-06, 2026-06-07

This study evaluated 115 gamete intrafallopian transfer cases, finding 36 pregnancies with the highest success rates in unexplained infertility and endometriosis, and noting associations between oocyte maturity, miscarriage, and multiple births.

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Abstract

The outcome of a series of 115 patients undergoing GIFT by minilaparotomy is described, their duration of infertility ranging between 3 and 19 years. Ovarian stimulation was carried out using clomiphene from day 3 and HMG from day 6, and HCG was used to induce follicular maturation. A maximum of four oocytes, two per oviduct with 100,000 spermatozoa, were replaced. Thirty-six pregnancies were established. The highest incidence of pregnancy was obtained in cases of unexplained infertility (42%) and endometriosis (28%), and the lowest with male factors (13%). The most mature oocytes gave the best results. There were eleven miscarriages (30.5%) and two ectopic pregnancies (5.5%). Eleven of the 23 deliveries involved multiple births.

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Condition tags

endometriosisinfertility

MeSH descriptors

Reproductive Techniques Adult Fallopian Tubes Female Humans Pregnancy

Citation neighborhood (sparse)

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Cited by (4)

Cited by (4)

Source provenance

europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:09:25.758913+00:00
License: CC0 · commercial use OK