Correction: Clinical presentation of perineal endometriosis and prognostic nomogram after surgical resection

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This correction notes that hormonal medication did not significantly interfere with perineal endometriosis recurrence risk, though intervention relieves symptoms and hormonal suppression may extend disease-free intervals without preventing recurrence.

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This document is a correction to Zhu et al.’s original BMC Women’s Health study on the clinical presentation of perineal endometriosis and a prognostic nomogram after surgical resection. The correction adds text to reference 32 in the original article, clarifying that in their study hormonal medication did not show a statistically significant association with recurrence risk, although pain in most recurrent cases improved after timely hormonal intervention; it also cites evidence that perineal endometriosis can regress after pregnancy and that GnRH-a inhibits lesions in a rat model but regrowth occurs after hormone cessation. The authors explicitly note that postoperative hormonal suppression may extend the disease-free interval without completely preventing recurrence. This paper is centrally about endometriosis — it is specifically a correction related to perineal endometriosis clinical presentation and prognostic nomogram after surgical resection.

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Zhu et al. BMC Women’s Health (2022) 22:500 https://doi.org/10.1186/s12905-022-02100-6 CORRECTION Correction: Clinical presentation of perineal endometriosis and prognostic nomogram after surgical resection Shiyang Zhu1,2,3†, Zhiyue Gu1,2†, Xiaoyan Li1,2, Yi Dai1,2, Jinghua Shi1,2 and Jinhua Leng1,2* © The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecom- mons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. Correction: BMC Women’s Health (2022) 22:476 https://doi.org/10.1186/s12905-022-02068-3 Following publication of the original article [1], In this article in text for ref. 32 has been inserted and the follow- ing is the text: In our study, hormonal medication did not seem to interfere with the risk of recurrence in a statistical signifi- cance way, which deviates from the rudimentary results that GnRH-a correlated with reduced recurrence in prior observations. However, after the diagnosis of recurrence, the pain symptom of most recurrent cases were well relieved after timely hormone intervention. Likewise, it has been reported that PEM lesions could spontane - ously regress after pregnancy, suggesting the hormone- responsive feature of the disease [30]. In agreement to our findings, Seong et  al. found hormone therapy was associated with longer recurrence-free interval from the time of surgery to the onset of recurrence after primary surgery for ovarian endometrioma [31]. Hormonal ther - apy maintains the minimal disease state by slowing down the regrowth rather than eliminate residuals, as revealed by Sharpe et  al. in a rat model that the implant lesion was significantly inhibited by GnRH-a while regrowth sustained spontaneously after the cessation of hormone suppressive treatment [32]. Taken together, these results suggest postoperative hormonal suppression has ben - eficial effects on extending disease-free interval but does not completely prevent recurrence of PEM. The original article has been corrected. Author details 1 Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan No. 1, Dongcheng District, Beijing 100730, China. 2 National Clinical Research Center for Obstetric and Gynecologic Diseases, Beijing, China. 3 Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, China. Accepted: 30 November 2022 Reference 1. Zhu S, Gu Z, Li X, et al. Clinical presentation of perineal endometriosis and prognostic nomogram after surgical resection. BMC Womens Health. 2022;22:476. https:// doi. org/ 10. 1186/ s12905- 022- 02068-3. Publisher’s Note Springer Nature remains neutral with regard to jurisdictional claims in pub- lished maps and institutional affiliations. Open Access The original article can be found online at https:// doi. org/ 10. 1186/ s12905- 022- 02068-3. †Shiyang Zhu and Zhiyue Gu have contributed equally to this work. *Correspondence: [email protected] 1 Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan No. 1, Dongcheng District, Beijing 100730, China Full list of author information is available at the end of the article

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