Hyperplastic processes in the endometrium: controversial and unresolved problems of the disease

E.G. Shvarev, L.V. Dikareva, A.R. Zoeva, O.G. Tishkova, O.E. Zaitseva, Yu.Yu. Ukhanova
In: Russian Bulletin of Obstetrician-Gynecologist · 2023 · vol. 23(4) , pp. 35 · doi:10.17116/rosakush20232304135 · W4386179660
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Abstract

The incidence of hormone-dependent tumors of reproductive organs, including endometrial hyperplastic processes, has been steadily increasing over the past decades. The data on statistical indices of the disease, data on its etiology and pathogenesis, approaches to early detection, treatment and estimation of its efficiency are still disputable and controversial. Endometrial hyperplastic processes are not only among the most common gynecological diseases, but in some cases they are the background to the development of precancerous lesions and endometrial cancer. In the absence of clinically relevant tumour markers for screening, this makes the problem of endometrial cancer particularly important. The presented review is devoted not only to the statement and clarification of some controversial aspects of the abovementioned pathology, but also to the description of the optimal combination of noninvasive and minimally invasive techniques to obtain sufficient information about its state and different approaches to the estimation of the efficacy of the carried out treatment.

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