Homeobox C6 is Up-Regulated and Affects the Pathogenesis of Endometriosis
HOXC6 was significantly up-regulated in ectopic endometriosis tissue and its down-regulation inhibited endometriotic stromal cell proliferation, adhesion, invasion, and migration via the TGF-β1/Smad pathway.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (30)
- An Integrated Genomic Approach Identifies HOXC8 as an Upstream Regulator in Ovarian Endometrioma via openalex
- Epithelial–Mesenchymal Transition in Endometriosis—When Does It Happen? via openalex
- Eutopic and ectopic stromal cells from patients with endometriosis exhibit differential invasive, adhesive, and proliferative behavior via openalex
- Identification of Candidate Gene Signatures and Regulatory Networks in Endometriosis and its Related Infertility by Integrated Analysis via openalex
- Insight into epigenetics of human endometriosis organoids: DNA methylation analysis of HOX genes and their cofactors via openalex
- Knockdown of vascular cell adhesion molecule 1 impedes transforming growth factor beta 1-mediated proliferation, migration, and invasion of endometriotic cyst stromal cells via openalex
- Pathophysiology, diagnosis, and management of endometriosis via openalex
- Research advances in endometriosis-related signaling pathways: A review via openalex
- The activation of TGF-β signaling promotes cell migration and invasion of ectopic endometrium by targeting NRP2 via openalex
- The role of the Hoxa10/HOXA10 gene in the etiology of endometriosis and its related infertility: a review via openalex
- Transforming growth factor beta1 from endometriomas promotes fibrosis in surrounding ovarian tissues via Smad2/3 signaling† via openalex
- W3149370098 via openalex
- W3165294846 via openalex
- W4226186497 via openalex
- W4229002066 via openalex
- W4234160457 via openalex
- W4289545130 via openalex
- W6640704600 via openalex
- W1946482308 via openalex
- W6807516075 via openalex
- W1966246416 via openalex
- W2089647590 via openalex
- W2132668492 via openalex
- W2150552506 via openalex
- W2173213419 via openalex
- W2204640292 via openalex
- W2783896058 via openalex
- W2901068426 via openalex
- W2904403641 via openalex
- W2953877825 via openalex
Source provenance
- europepmc
- last seen: 2026-06-11T06:19:48.454388+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-29T00:31:17.205936+00:00