Conservative Management of Ovarian Fibroma in A Case of Gorlin-Goltz Syndrome Comorbid with Endometriosis.

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This case report details the conservative surgical management of bilateral ovarian fibromas in a 25-year-old woman with Gorlin-Goltz syndrome and endometriosis, highlighting fertility preservation.

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AI-generated deep summary by claude@2026-06, 2026-06-09 · read from full text

This paper is a case report describing a 25-year-old woman with Gorlin-Goltz syndrome who had bilateral ovarian fibromas along with endometriosis and a septated uterus, presenting with facial asymmetry from recurrent odontogenic keratocysts. The authors highlight that ovarian fibromas are often difficult to diagnose preoperatively and note the possibility of Gorlin-Goltz syndrome in bilateral cases. They report conservative surgical management aimed at preserving ovarian function and fertility in a young patient. This paper is centrally about endometriosis — it describes a Gorlin-Goltz syndrome case that is comorbid with endometriosis.

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Abstract

Ovarian fibromas are the most common benign solid ovarian tumors, which are often difficult to diagnose preoperatively. Ovarian fibromas, especially in bilateral cases, may be cases of Gorlin-Goltz syndrome (GGS), a rare autosomal dominant disorder with predisposition to basal cell carcinomas (BCCs) and other various benign and malignant tumors. This case report describes a 25 year-old female with GGS, bilateral ovarian fibroma, endometriosis and septated uterus, which was referred to the Gynecology Clinic of Rasoul-e-Akram Hospital in October 2016. This patient had facial asymmetry due to recurrent odontogenic keratocysts. In young cases of ovarian fibromas as reported here, conservative surgical management can preserve ovarian function and fertility. These patients must be followed up by a multidisciplinary team and submitted to periodic tests.
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International Journal of Fertility and Sterility (Apr 2018) Conservative Management of Ovarian Fibroma in A Case of Gorlin-Goltz Syndrome Comorbid with Endometriosis Abstract Ovarian fibromas are the most common benign solid ovarian tumors, which are often difficult to diagnose preoperatively. Ovarian fibromas, especially in bilateral cases, may be cases of Gorlin-Goltz syndrome (GGS), a rare autosomal dominant disorder with predisposition to basal cell carcinomas (BCCs) and other various benign and malignant tumors. This case report describes a 25 year-old female with GGS, bilateral ovarian fibroma, endometriosis and septated uterus, which was referred to the Gynecology Clinic of Rasoul-e-Akram Hospital in October 2016. This patient had facial asymmetry due to recurrent odontogenic keratocysts. In young cases of ovarian fibromas as reported here, conservative surgical management can preserve ovarian function and fertility. These patients must be followed up by a multidisciplinary team and submitted to periodic tests. Keywords

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endometriosis

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