El papel de los biomarcadores en el diagnóstico precoz de la endometriosis

Manuel Alejandro Cordones Sevillano, Kenya Andreina Recalde Dicado, Shirley Natali Lema Sarmiento, Alex Moran
In: RECIAMUC · 2019 · vol. 3(1) , pp. 196–213 · doi:10.26820/reciamuc/3.(2).abril.2019.196-213 · W2984620756
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⚙ AI-generated summary by claude@2026-07, 2026-07-09 ⓘ

This review examines potential biomarkers and research for the early diagnosis of endometriosis, a chronic gynecological condition often diagnosed late.

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⚙ AI-generated deep summary by claude@2026-07, 2026-07-09 · read from full text ⓘ

This paper is a review discussing the role of biomarkers and related research approaches for early diagnosis of endometriosis, emphasizing that chronic symptoms often lead to substantial diagnostic delays and consequent psychological and physical harm. It surveys biomarker categories and diagnostic investigations, including prior literature on CA-125 performance, cervical mucus proteomics, microRNAs, antibodies, and imaging accuracy, while highlighting the continuing challenge that traditional methods have produced poor diagnostic results. As a review, it does not present new patient-level data and is limited by the heterogeneity of included studies and diagnostic modalities. Relevance to endometriosis: the paper’s sole topic is the role of biomarkers in the early diagnosis of endometriosis, focusing specifically on biomarker-based strategies to address diagnostic delay.

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Abstract

La endometriosis es un problema ginecológico crónica que es frecuente en la población general. Debido a sus variadas presentaciones a menudo hay un gran retraso en el diagnóstico lo que conlleva a incurrir en una gran cantidad de daño psicológico y físico con la infertilidad como una de las desafortunadas secuelas. Si bien se han realizado mejoras en relación con el tratamiento de la endometriosis, el diagnóstico sigue siendo un reto para los médicos con las investigaciones tradicionales que producen malos resultados. Esta revisión considerará biomarcadores potenciales e investigaciones para el diagnóstico precoz de la endometriosis.
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El papel de los biomarcadores en el diagnóstico precoz de la endometriosis DOI: https://doi.org/10.26820/reciamuc/3.(2).abril.2019.196-213Resumen La endometriosis es un problema ginecológico crónica que es frecuente en la población general. Debido a sus variadas presentaciones a menudo hay un gran retraso en el diagnóstico lo que conlleva a incurrir en una gran cantidad de daño psicológico y físico con la infertilidad como una de las desafortunadas secuelas. Si bien se han realizado mejoras en relación con el tratamiento de la endometriosis, el diagnóstico sigue siendo un reto para los médicos con las investigaciones tradicionales que producen malos resultados. Esta revisión considerará biomarcadores potenciales e investigaciones para el diagnóstico precoz de la endometriosis. Descargas Citas A, Fassbender., RO Burney, T D’Hooghe, y L. Giudice. «Update on biomarkers for the detection of endometriosis. » Biomed Res Int, 2015. Bolívar, J. Investigación Documental. México.Pax, 2015. Borghese, B, KT Zondervan, MS Abrao, C Chapron, y D. Vaiman. «Recent insights on the genetics and epigenetics of endometriosis. » Clinical Genetics., 2016: 254-264. Castro, J. Técnicas Documentales. México. Limusa, 2016. Cosar, E, R Mamillapalli, GS Ersoy, S Cho, y B. Seife. « Serum microRNAs as diagnostic markers of endometriosis: a comprehensive array based analysis. » Fertil Steril, 2016: 402-409. Das, PM, y JR. Bast. « Early detection of ovarian cancer. » Biomark Med, 2008: 291-303. Davila, A. Concepto de terminos cientificos. Caracas: Oasis, 2015. Grande, G, F Vincenzoni, D Milardi, G Pompa, y D. Ricciardi. «Cervical mucus proteome in endometriosis. 14: 7. » Clin Proteomics, 2017: 7-14. Guerriero, S, S Ajossa, J Minguez, M Jurado, y V. Mais. «Accuracy of transvaginal ultrasound for diagnosis of deep endometriosis in uterosacral ligaments, rectovaginal septum, vagina and bladder. » Ultrasound Obstet Gynecol, 2015: 534-545. Gupta, S, A Agarwal, L Sekhon, N Krajcir, Cocuzza, y M. «Serum and peritoneal abnormalities in endometriosis: potential use as diagnostic markers. » Minerva Ginecol, 2006: 527-551. Hsu, AL, I Khachikyan, Stratton, y P. «Invasive and non-invasive methods for the diagnosis of endometriosis.» Clin Obstet Gynecol , 2011: 53. Miller, EJ, y IS. Fraser. «The importance of pelvic nerve fibres in endometriosis.» Women’s health , 2015: 611-618. Mol, BW, N Bayram, JG Lijmer, MA Wiegerinck, y MY. Bongers. «The performance of CA-125 measurement in the detection of endometriosis: a meta-analysis.» Fertil Steril , 1998: 1101-1108. Oliveria, M, T Raymundo, L Soares, T Pereira, y A. Demôro. «How to use CA-125 more effectively in the diagnosis of deep endometriosis. .» BioMed Research International, 2017: 6. Randall, GW, PA Gantt, RL Poe Zeigler, CA Bergmann, y ME. Noel. «Serum antiendometrial antibodies and diagnosis of endometriosis.» Reprod Immunol, 2007: 374-382. Riazi, H, N Tehranian, S Ziaei, E Mohammadi, y E. Hajizadeh. «Clinical diagnosis of pelvic endometriosis: a scoping review. .» BMC Womens Health, 2015: 15-39. Tadros, M, y N. Keriakos. «Diffusion MRI versus ultrasound in How to cite this article: Dominic A W. The Role of Biomarkers in the Early Diagnosis of Endometriosis. .» Invest Gynecol Res Women’s Health and Nuclear Medicine, 2016: 1765-1771.

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