Neuromodulation for Chronic Pelvic Pain

Jessica C. Lloyd, Courtenay Moore
In: Adult and Pediatric Neuromodulation · 2018 · pp. 105–117 · doi:10.1007/978-3-319-73266-4_8 · W2794014308
book-chapter OA: closed CC0
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-08 ⓘ

Neuromodulation is considered for chronic pelvic pain due to dysregulated central nervous system responses, with sacral neuromodulation aiming to balance impulses but requiring more rigorous trials to validate its effectiveness and optimal approach.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 ⓘ

This paper is a narrative review of chronic pelvic pain, discussing proposed mechanisms involving dysregulated central nervous system responses to non-noxious stimuli and the roles of sympathetic, parasympathetic, and somatic pelvic innervation, with a focus on sacral neuromodulation as a possible multimodal treatment. It reports that studies have shown pain improvement in some patients, but emphasizes that much of the evidence consists of small and non-randomized studies, leaving generalization difficult and creating ongoing controversy about which pelvic nerves to target and whether bilateral stimulation is superior to unilateral stimulation. The paper calls for large-scale randomized trials with strict inclusion criteria and long-term follow-up to evaluate sacral neuromodulation for chronic pelvic pain more rigorously. Relevance to endometriosis: it does not specifically discuss endometriosis in the provided text, but it is included in the corpus because it addresses chronic pelvic pain and sacral neuromodulation approaches that overlap with pelvic pain conditions relevant to endometriosis.

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chronic_pelvic_pain

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last seen: 2026-06-10T17:14:06.276822+00:00
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