Progesterone receptor +331G/A polymorphism in endometriosis and deep-infiltrating endometriosis

Davide Gentilini, Paola Viganò, Paola Vigano, Luca Carmignani, Carmignani L, Spinelli M, Matteo Giulio Spinelli, Matteo Spinelli, Mauro Busacca, Busacca M, Di Blasio AM, Anna Maria Di Blasio
Fertility and sterility · 2008 · vol. 90(4) , pp. 1243–1245 · doi:10.1016/j.fertnstert.2007.11.034 · PMID:18281038 · W2156768103
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This study investigated the association between the progesterone receptor +331G/A polymorphism and the risk of endometriosis, including deep-infiltrating endometriosis.

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Abstract

In this study, we sought to examine the association between P receptor +331G/A polymorphism and endometriosis. We excluded any relationship between endometriosis in general and the P receptor +331G/A polymorphism but found a significant association with deep-infiltrating endometriosis, supporting a potential role of this variant in the P receptor-dependent invasive behavior of endometrial cells.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Polymorphism, Single Nucleotide Receptors, Progesterone Risk Assessment Endometriosis Endometriosis Endometriosis Female Female Genetic Predisposition to Disease Genetic Predisposition to Disease Genetic Predisposition to Disease Genetic Predisposition to Disease Heterozygote Heterozygote Humans Humans Italy Italy

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References (16)

Cited by (8)

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