Progesterone Receptor Gene Polymorphism Promoter Region +331G/A Increases Risk of Endometriosis
article
OA: gold
CC0
AI-generated summary
This case-control study found that the progesterone receptor gene polymorphism promoter region +331G/A genotype significantly increases the risk of endometriosis.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
Objective: To identify relationship between progesterone receptor
gene polymorphism promoter region +331G/A with the risk of
endometriosis.
Method: An observational case-control study. Population are women
with endometriosis and/or adenomyosis who have been performed
laparotomy/laparoscopy at Obstetrics and Gynecology
Department Dr. Mohammad Hoesin General Hospital Palembang,
January-November 2013. Subjects fulfilled inclusion criteria, given
informed consent and performed blood sampling continued by PCRRFLP.
Results were divided into A/A genotype (homozygote mutant),
G/A (heterozygote mutant), and G/G (homozygote wild type).
Data were analyzed by SPSS 21.0 version.
Result: PCR-RFLP results for+331G/A genotype were 26 (54.1%) in
case group and 14 (26.4%) in control. +331A/A genotype was not
found in both groups. There was significant increase risk of endometriosis
in women carrying genotype +331G/A to those with genotype
+331G/G with OR 3.29 (p
My notes (saved in your browser only)
Condition tags
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (11)
- Association between polymorphisms in the progesterone receptor gene and endometriosis via openalex
- Pathogenesis of endometriosis: natural immunity dysfunction or autoimmune disease? via openalex
- Pathogenesis of endometriosis: the role of genetics, inflammation and oxidative stress via openalex
- Progesterone receptor +331G/A polymorphism in endometriosis and deep-infiltrating endometriosis via openalex
- Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis via openalex
- Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis1 via openalex
- Progesterone receptor polymorphism +331G/A is associated with a decreased risk of deep infiltrating endometriosis via openalex
- Role of some biomarkers in chronic pelvic pain for early detection of endometriosis in infertile women via openalex
- W2155024696 via openalex
- W2033143591 via openalex
- W4214765616 via openalex
Source provenance
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0
· commercial use OK