Composite tumor consisting of dermatofibrosarcoma protuberans and giant cell fibroblastoma associated with intratumoral endometriosis. Report of a case

Kholová I, I Kholová, Ivana Kholová, Aleš Ryška, A Ryska, K Dědič, K Dedic, Dedic K
Pathology, research and practice · 2001 · vol. 197(4) , pp. 263–267 · doi:10.1078/0344-0338-00045 · PMID:11358013 · W1970431398
Case report OA: closed CC0 ⤵ 4 in-corpus citations
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This case report describes a rare composite tumor containing dermatofibrosarcoma protuberans and giant cell fibroblastoma, which was incidentally found to be associated with intratumoral endometriosis.

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Abstract

We present a unique case of composite skin tumor of the vulva consisting of dermatofibrosarcoma protuberans (DFSP) and giant cell fibroblastoma (GCF) with an intratumoral focus of endometriosis. A 31-year-old female with a 10-year-history of a recurring subcutaneous tumor in the vulvar area underwent excision of the seventh recurrence of the tumor. Microscopic examination revealed a composite fibrohistiocytic tumor consisting of DFSP and GCF. Additionally, a focus of endometriosis within the tumor tissue was found. Malignant transformation of extragonadal endometriosis has already been described; we present, however, the occurrence of a focus of endometriosis within the tissue of a hormonally independent soft tissue tumor. There is a possible link to the occurrence of cutaneous endometriosis at previous surgery sites and in the scars. The presence of endometriosis within the soft tissue tumor represents, to the best of our knowledge, a previously undescribed collision phenomenon.

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Condition tags

endometriosis

MeSH descriptors

Dermatofibrosarcoma Endometriosis Fibroma Giant Cell Tumors Neoplasms, Multiple Primary Soft Tissue Neoplasms Adult Adult Antigens, Neoplasm Antigens, Neoplasm Antigens, Neoplasm Biomarkers, Tumor Biomarkers, Tumor Biomarkers, Tumor Dermatofibrosarcoma Dermatofibrosarcoma Dermatofibrosarcoma Dermatofibrosarcoma Endometriosis Endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (31)

Cited by (4)

Source provenance

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