Psychosexual health 5 years after hysterectomy: population-based comparison with endometrial ablation for dysfunctional uterine bleeding

Klim McPherson, Aleks Herbert, A. Herbert, Andrew Judge, Aileen Clarke, Stephen Bridgman, Michael Maresh, M Maresh, C. Overton, Chris Overton
Health expectations : an international journal of public participation in health care and health policy · 2005 · vol. 8(3) , pp. 234–243 · doi:10.1111/j.1369-7625.2005.00338.x · PMID:16098153 · PMC5060293 · W2105360855
Observational OA: bronze CC0 ⤵ 16 in-corpus citations
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Five years after surgery for dysfunctional uterine bleeding, hysterectomy was associated with a higher prevalence of psychosexual problems, particularly vaginal dryness and loss of libido, compared to endometrial ablation, with concurrent oophorectomy exacerbating these issues.

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Abstract

BACKGROUND: We report a population-based comparison of psychosexual health 5 years after contrasting amounts of surgical treatments for heavy periods [dysfunctional uterine bleeding (DUB)]. Women's fears about sexual function after hysterectomy might not be unfounded. The psychosexual problems may return and/or develop with time. The removal of ovaries at the time of hysterectomy is associated with greater deterioration of self-reported sexual function. Surgical menopause significantly impairs sexual wellbeing. We failed to observe uniform beneficial effects of hormone replacement therapy (HRT) on reported psychosexual health. OBJECTIVE: To compare self-reported bothersome sexual function; loss of interest in sex, difficulty in becoming sexually excited and vaginal dryness 5 years after surgical management of DUB [transcervical endometrial resection/ablation (TCRE) or subtotal and total hysterectomy, with and without prophylactic bilateral oophorectomy (BO)]. DESIGN: Prospective cohort study up to 5 years post-surgery for DUB, TCRE or hysterectomy, with or without BO. SETTING: Over 400 NHS and private hospitals in England, Northern Ireland and Wales. COHORT: Of 11,325 women who responded to the 5-year questionnaire, over 9500 (84%) were valid cases, and over 8900 (94%) did complete the questions relating to psychosexual function. Most were between the ages of 39 and 45 years, married or cohabiting. MAIN OUTCOMES: Self-reported experience of bother, recorded as 'some', 'severe' and 'extreme', to questions on (1) libido loss, (2) difficulty with sexual arousal, and (3) vaginal dryness during the past 4 weeks, 5 years after surgery. RESULTS: Five years after surgery for DUB, the crude and adjusted prevalence of psychosexual problems was higher after hysterectomy than after TCRE. Amongst the women with concurrent BO, the age- and HRT-adjusted odds ratios for extreme psychosexual problems were increased by 80% (libido loss), 82% (difficult sex arousal) and 69% (vaginal dryness) compared with TCRE. CONCLUSIONS: Five years after hysterectomy more women reported having bothersome psychosexual function than did the women who had a less invasive operation. Hormone therapy, although related to surgical method, did not reduce this long-term detrimental effect. The odds were particularly high amongst women with concurrent BO. Women should be advised that they might be at higher risk of psychosexual problems following hysterectomy, compared with a less invasive procedure.

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MeSH descriptors

Catheter Ablation Hysterectomy Menorrhagia Sexual Behavior Sexual Dysfunctions, Psychological Adult Catheter Ablation Catheter Ablation Endometrium Endometrium Estrogen Replacement Therapy Female Humans Hysterectomy Hysterectomy Libido Menorrhagia Middle Aged Outcome Assessment, Health Care Ovariectomy

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