HUBUNGAN USIA MENARCHE DENGAN KEJADIAN ENDOMETRIOSIS

Sri Purwati Puji Lestari, Jimmy Yanuar Annas, Juniastuti Juniastuti
In: Indonesian Midwifery and Health Sciences Journal · 2021 · vol. 3(1) , pp. 30–36 · doi:10.20473/imhsj.v3i1.2019.30-36 · W3193200178
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This retrospective case-control study found no significant association between age of menarche and the incidence of endometriosis in women at Dr. Ramelan Hospital Surabaya.

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This retrospective case-control study examined whether age at menarche is associated with the incidence of endometriosis among women in Dr. Ramelan Hospital Surabaya, comparing 35 surgical cases confirmed by anatomical pathology to 35 controls undergoing laparoscopic tubal ligation. Using purposive sampling from 2017–2018, the authors analyzed the data with a chi-square test at α = 0.05 and found that most endometriosis cases reported menarche at ages 12–13 (62.9%). The study reported no significant association between age at menarche and endometriosis incidence (p = 0.484). This paper is centrally about endometriosis — it specifically tests the relationship between age at menarche and endometriosis occurrence.

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Abstract

AbstrakLatar belakang : Endometriosis adalah penyakit ginekologi yang bersifat menahun dan progresif dengan angka kejadiannya mengalami peningkatan dari tahun ke tahun namun penyebabnya sebagian besar masih belum diketahui. Usia menarche adalah salah satu faktor resiko yang berhubungan dengan kejadian endometriosis. Tujuan penulisan ini adalah untuk mengetahui hubungan antara usia menarche dengan kejadian endometriosis di Rumkital Dr. Ramelan Surabaya. Metode : Penelitian ini merupakan penelitian analitik retrospective dengan pendekatan case control. Kelompok kasus adalah wanita yang telah menjalani operasi kandungan dengan hasil Patologi Anatomi menunjukkan endometriosis dan kelompok kontrol adalah pasien wanita yang telah menjalani operasi laparaskopi MOW (Metode Opetratif Wanita). Sampel yang diambil sebanyak 70 responden (35 kasus, 35 kontrol) selama periode tahun 2017-2018 dengan teknik purposive sampling berdasarkan kriteria inklusi.. Analisa data menggunakan uji chi square pada tingkat kemaknaan α 0,05. Hasil : Responden dengan endometriosis sebagian besar mengalami menarche pada usia 12-13 tahun (62,9%). Usia menarche tidak memiliki hubungan yang signifikan dengan kejadian endometriosis (p=0,484). Kesimpulan: Tidak ada hubungan antara usia menarche dengan kejadian endometriosis di Rumkital Dr. Ramelan Surabaya. AbstractBackground: Endometriosis is a chronic and progressive gynecological disease with an increased incidence every year but the cause is largely unknown. Age of menarche is one of the risk factors associated with the incidence of endometriosis. The purpose of this study was to determine the association between age of menarche the incidence of endometriosis in Dr. Ramelan Hospital Surabaya. Method: This was a retrospective analytic study with a case control approach. The case group was women who had undergone uterine surgery with Anatomical Pathology results showing endometriosis and the control group were women who had undergone laparoscopic tuba ligation. 70 respondents (35 cases, 35 controls) taken during the period of 2017-2018 with a purposive sampling technique based on inclusion criteria. Analyzed data used chu square test at significant level of α 0,05. Results: Most respondent who got endometriosis had menarche at 12-13 years old (62.9%). The age of menarche had no significant association with the incidence of endometriosis (p = 0.484). Conclusion: We found no association between age of menarche and the incidence of endometriosis with the incidence of endometriosis in the Dr. Ramelan Hospital Surabaya.
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HUBUNGAN USIA MENARCHE DENGAN KEJADIAN ENDOMETRIOSIS Downloads Abstrak Latar belakang : Endometriosis adalah penyakit ginekologi yang bersifat menahun dan progresif dengan angka kejadiannya mengalami peningkatan dari tahun ke tahun namun penyebabnya sebagian besar masih belum diketahui. Usia menarche adalah salah satu faktor resiko yang berhubungan dengan kejadian endometriosis. Tujuan penulisan ini adalah untuk mengetahui hubungan antara usia menarche dengan kejadian endometriosis di Rumkital Dr. Ramelan Surabaya. Metode : Penelitian ini merupakan penelitian analitik retrospective dengan pendekatan case control. Kelompok kasus adalah wanita yang telah menjalani operasi kandungan dengan hasil Patologi Anatomi menunjukkan endometriosis dan kelompok kontrol adalah pasien wanita yang telah menjalani operasi laparaskopi MOW (Metode Opetratif Wanita). Sampel yang diambil sebanyak 70 responden (35 kasus, 35 kontrol) selama periode tahun 2017-2018 dengan teknik purposive sampling berdasarkan kriteria inklusi.. Analisa data menggunakan uji chi square pada tingkat kemaknaan α 0,05. Hasil : Responden dengan endometriosis sebagian besar mengalami menarche pada usia 12-13 tahun (62,9%). Usia menarche tidak memiliki hubungan yang signifikan dengan kejadian endometriosis (p=0,484). Kesimpulan: Tidak ada hubungan antara usia menarche dengan kejadian endometriosis di Rumkital Dr. Ramelan Surabaya. Abstract Background: Endometriosis is a chronic and progressive gynecological disease with an increased incidence every year but the cause is largely unknown. Age of menarche is one of the risk factors associated with the incidence of endometriosis. The purpose of this study was to determine the association between age of menarche the incidence of endometriosis in Dr. Ramelan Hospital Surabaya. Method: This was a retrospective analytic study with a case control approach. The case group was women who had undergone uterine surgery with Anatomical Pathology results showing endometriosis and the control group were women who had undergone laparoscopic tuba ligation. 70 respondents (35 cases, 35 controls) taken during the period of 2017-2018 with a purposive sampling technique based on inclusion criteria. Analyzed data used chu square test at significant level of α 0,05. Results: Most respondent who got endometriosis had menarche at 12-13 years old (62.9%). The age of menarche had no significant association with the incidence of endometriosis (p = 0.484). Conclusion: We found no association between age of menarche and the incidence of endometriosis with the incidence of endometriosis in the Dr. Ramelan Hospital Surabaya. Bouzari, Z., Yazdani, S., Aharngarkolaee, ZH., Zeinalzadeh, M & Hajian, K. (2016). The Comparison of Menstrual Characteristics and BMI in Women with Endometriosis and Without Endometriosis. Women's health & gynecology, 2(8), pp 1-6. European Society of Human Reproduction and Embriology (ESHRE). (2013). Guideline : management of women with endometriosis. ESHRE endometriosis guideline development group. [online] diperoleh dari https://www.eshre.eu/Guidelines-and-Legal [diakses pada 12 februari 2019]. Gaudineau, A., Ehlinger, V., Vayssiere, C. et al. (2010). Factors associated with early menarche : result from the French health behavior in school-aged children (HBSC) study. BMC public health, 10 : 175, pp.1-2. Hediger, M.L., Hartnett, H.J., Louis, G.M.B. (2005). Association of endometriosis with body size and figure. Fertility and sterility, 84(5), pp. 1366-1374. Hestiantoro, A., Natadisastra, M., Wiweko, B. dkk. (2013). Current updates on polycystic ovary syndrome, endometriosis, adenomyosis. Jakarta : Sagung seto. Hlm 73-102. Jacoeb, T.Z. & Hadisaputra, W. (2009). Penanganan endometriosis panduan klinis dan algoritme. Jakarta : CV. Sagung Seto. Liu, Yong & Zhang, Weiyuan. (2017). Association between body mass index and endometriosis risk : a meta-analysis. Oncotarget, 8(29), pp. 46928-46936. Mukti, P. (2014). Faktor risiko kejadian endometriosis. Unnes journal of public health, 3 (3), pp 1-10. http://journal.unnes.ac.id/sju/index.php/ujph Nnoaham, K. E., Webster, P., Kumbang, J., Kennedy, S. H., & Zondervan, K. T. (2012). Is early age at menarche a risk factor for endometriosis? A systematic review and meta-analysis of case-control studies. Fertility and sterility, 98(3), 702–712.e6. doi:10.1016/j.fertnstert.2012.05.035 Peterson, C.M., Johnstone, E.B., Hammoud, A. O. et al. (2013). Risk factors associated with endometriosis : importance of study population for characterizing disease in the ENDO study. American journal of obstetrics and gynecology, 208 (6), pp. 451 e1-451 e11. DOI:10.1016/j.ajog.2013.02.040 Saha, R., Kuja-Halkola, R., Tornvall, P & Marions, L. (2017). Reproductive and lifestyle factors associated endometriosis in a large cross-sectional population sample. Journal of women's health, 26 (2), pp. 152-158. Sohn, K. (2015). The trend in age at menarche in Indonesia : birth cohorts 1944-1988. Journal of biosocial science, 47 (3), pp. 407-412. Speroff, Lion & Fritz, M.A. (2011). Clinical gynesology and infertility 8th edition. Philadelphia : Wolters Kluwer Lippincott Williams & Wilkins. pp. 1233-1234. Treolar, S.A., Bell, T.A., Nagle, C.M. et al. (2010). Early menstrual characteristic associated with subsequent diagnosis of endometriosis. American journal of obstetrics and gynecology, 202 (6), pp. 534 e1-534 e6. DOI: https://doi.org/10.1016/j.ajog.2009.10.857 Yamamoto, A., Johnstone, E.B., Bloom, M.S. et al. (2017). A higher prevalence of endometriosis among asian women does not contribute to poorer IVF outcomes. Journal of assisted reproduction and genetics, 34 (6), pp. 765-774. 1. The journal allows the author to hold the copyright of the article without restrictions. 2. The journal allows the author(s) to retain publishing rights without restrictions 3. The formal legal aspect of journal publication accessibility refers to Creative Commons Atribution-Share Alike 4.0 (CC BY-SA). This Journal (e-ISSN 2656-7806) is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

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