LONG-TERM RESULTS AFTER LAPAROSCOPIC INTERVENTIONS IN PATIENTS WITH CONCOMITANT ENDOMETRIOSIS AND ADENOMYOSIS

ZUMRUD F. MAHMUDBEYOVA
In: EXPERIMENTAL & CLINICAL MEDICINE GEORGIA · 2023 · doi:10.52340/jecm.2023.05.06 · W4387608950
Observational OA: bronze CC0
🔓 Open OA copy Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-10 ⓘ

Laparoscopic intervention for endometriosis and adenomyosis patients revealed increased long-term dysmenorrhea, dyspareunia, and pelvic pain, with a lower pregnancy rate in those with concomitant adenomyosis.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 · read from full text ⓘ

This retrospective study assessed long-term postoperative outcomes about 5 years after laparoscopic surgery in 109 women treated for chronic pelvic pain, ovarian cystectomy, hysterectomy, or myomectomy, stratifying them by the presence or absence of concomitant adenomyosis. Stage I–IV endometriosis was distributed across the cohort, and women with endometriosis plus adenomyosis (n=50) had significantly higher VAS pain scores, with higher dysmenorrhea and dyspareunia compared with women with endometriosis alone (n=59), while pregnancy was less frequent in the adenomyosis group. A caveat explicitly implied by the design is that outcomes are observational and tied to varied surgical indications, limiting causal inference and generalizability. This paper is centrally about endometriosis and adenomyosis—specifically long-term outcomes after laparoscopic interventions in patients with concomitant endometriosis and adenomyosis.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

The aim of the study was to evaluate postoperative outcomes in patients with endometriosis and adenomyosis. The study involved 109 women who had laparoscopic surgery 5 years ago for: chronic pelvic pain – in 29.4%, cystectomy – in 26.6%, hysterectomy – in 22.9%, myomectomy – in 21.1% patients. Stage I endometriosis was observed in 27.5%, stage II – in 26.6%, stage III – in 25.7%, stage IV – in 20.2% of patients. Concomitant adenomyosis occurs in patients with 3rd and 4th degree of severity of endometriosis. The patients were divided into 2 groups: group I - 59 patients with endometriosis without adenomyosis; group II - 50 patients with endometriosis and adenomyosis. There were no significant differences in average age, body mass index, parity and cases of pelvic pain between the groups. In group II patients, on average, the score on the VAS scale is significantly higher (p=0.045). In group II, dysmenorrhea was higher by 27.1% (p=0.038), dyspareunia – by 48.3% (p=0.042). The chance of developing dysmenorrhea among patients with endometriosis and adenomyosis is 2.3 times higher (OR=0.431, 95% CI 0.193-0.906, p<0.05); dyspareunia is 2.5 times higher (OR=0.407, 95%CI 0.170-0.976, p0.05). Out of 109 patients, 44.0% of women became pregnant, of which 19.3% had live children. In group II, the number of pregnancies was lower (χ2=3.776, p=0.052). Thus, in the long-term period after laparoscopic intervention, the probability of developing dysmenorrhea, dyspareunia, pelvic pain is high in women with endometriosis and adenomyosis, and the frequency of pregnancy was lower. We consider it appropriate to find such patients under close supervision after surgery.
Full text 5,760 characters · extracted from oa-doi-fallback · click to expand
LONG-TERM RESULTS AFTER LAPAROSCOPIC INTERVENTIONS IN PATIENTS WITH CONCOMITANT ENDOMETRIOSIS AND ADENOMYOSIS DOI: https://doi.org/10.52340/jecm.2023.05.06Keywords: laparoscopic intervention, endometriosis, adenomyosis, complicationsAbstract The aim of the study was to evaluate postoperative outcomes in patients with endometriosis and adenomyosis. The study involved 109 women who had laparoscopic surgery 5 years ago for: chronic pelvic pain – in 29.4%, cystectomy – in 26.6%, hysterectomy – in 22.9%, myomectomy – in 21.1% patients. Stage I endometriosis was observed in 27.5%, stage II – in 26.6%, stage III – in 25.7%, stage IV – in 20.2% of patients. Concomitant adenomyosis occurs in patients with 3rd and 4th degree of severity of endometriosis. The patients were divided into 2 groups: group I - 59 patients with endometriosis without adenomyosis; group II - 50 patients with endometriosis and adenomyosis. There were no significant differences in average age, body mass index, parity and cases of pelvic pain between the groups. In group II patients, on average, the score on the VAS scale is significantly higher (p=0.045). In group II, dysmenorrhea was higher by 27.1% (p=0.038), dyspareunia – by 48.3% (p=0.042). The chance of developing dysmenorrhea among patients with endometriosis and adenomyosis is 2.3 times higher (OR=0.431, 95% CI 0.193-0.906, p<0.05); dyspareunia is 2.5 times higher (OR=0.407, 95%CI 0.170-0.976, p0.05). Out of 109 patients, 44.0% of women became pregnant, of which 19.3% had live children. In group II, the number of pregnancies was lower (χ2=3.776, p=0.052). Thus, in the long-term period after laparoscopic intervention, the probability of developing dysmenorrhea, dyspareunia, pelvic pain is high in women with endometriosis and adenomyosis, and the frequency of pregnancy was lower. We consider it appropriate to find such patients under close supervision after surgery. Downloads References Boucher A, Brichant G, Gridelet V, Nisolle M, Ravet S, Timmermans M, et al. Implantation Failure in Endometriosis Patients: Etiopathogenesis. J. Clin. Med. 2022;11(18):5366. doi: 10.3390/jcm11185366. Brichant G, Moïse A, Nisolle M. L’endométriose est-elle une pathologie inflammatoire? [Endometriosis as an inflammatory disease?]. Rev Med Liege. 2022;77(5-6):370-376. Habiba M, Benagiano G. Classifying Adenomyosis: Progress and Challenges. Int J Environ Res Public Health. 2021;18(23):12386. doi: 10.3390/ijerph182312386. Hui Y, Zhao S, Gu J, Hang C. Analysis of factors related to fertility after endometriosis combined with infertility laparoscopic surgery. Medicine (Baltimore). 2020; 99(21):e20132. doi: 10.1097/MD.0000000000020132. Kobayashi H, Matsubara S, Imanaka S. Clinicopathological features of different subtypes in adenomyosis: Focus on early lesions. PLoS One. 2021; 16(7):e0254147. doi: 10.1371/journal.pone.0254147. Li XY, Chao XP, Leng JH, Zhang W, Zhang J-Ji, Dai Y, et al. Risk factors for postoperative recurrence of ovarian endometriosis: long-term follow-up of 358 women. J Ovarian Res. 2019; 12:79. doi: 10.1186/s13048-019-0552-y. Mooney SS, Ross V, Stern C, Rogers PAW, Healey M. Obstetric Outcome After Surgical Treatment of Endometriosis: A Review of the Literature. Front Reprod Health. 2021; 3:750750. doi: 10.3389/frph.2021.750750. Parkin KL, Fazleabas AT. Uterine Leukocyte Function and Dysfunction: A Hypothesis on the Impact of Endometriosis. Am. J. Reprod. Immunol. 2016; 75:411–417. doi: 10.1111/aji.12487. Piriyev E, Schiermeier S, Römer T. Laparoscopic Approach in Bladder Endometriosis, Intraoperative and Postoperative Outcomes. In Vivo. 2023; 37(1): 357-365. doi: 10.21873/invivo.13086. Rad MT, Akpinar-Isci D, Nobs T, Gasimli K, Becker S. Pregnancy after laparoscopic surgery for endometriosis: How long should we wait? A retrospective study involving a long-term follow up at a university endometriosis center. International Journal of Gynecology & Obstetrics. 2023. doi: 10.1002/ijgo.14849. Ratner RT, Harris A, Tsaltas J, Goyal N, Davies-Tuck M, Najjar H, et al. An eight-year retrospective analysis of laparoscopic surgery for endometriosis, outcomes and complications in a large multicenter unit. Clin. Exp. Obstet. Gynecol. 2019;46(5):699–703. doi: 10.12891/ceog4949.2019. Sun T-T, Li X-Y, Shi J-H, Wu Y-S, Gu Z-Y, Leng J-H. Clinical Features and Long-Term Outcomes After Laparoscopic Surgery in Patients Co-existing With Endometriosis and Adenomyosis. Front. Med. 2021; 8:696374. doi: 10.3389/fmed.2021.696374. Timmermans M, Nisolle M, Brichant G, Henry L, Gillet E, Kellner B, et al. Impact of Adenomyosis and Endometriosis on Chronic Pelvic Pain after Niche Repair. J. Clin. Med. 2023;12(10):3484. doi: 10.3390/jcm12103484. Upson K, Missmer SA. Epidemiology of Adenomyosis. Semin Reprod Med. 2020;38(2-03):89-107. doi: 10.1055/s-0040-1718920. Wang Y, Yi YC, Guu HF, Chen YF, Kung HF, Chang JC, et al. Impact of adenomyosis and endometriosis on IVF/ICSI pregnancy outcome in patients undergoing gonadotropin-releasing hormone agonist treatment and frozen embryo transfer. Sci Rep. 2023;13(1):6741. doi: 10.1038/s41598-023-34045-7. Yang X, Bao M, Hang T, Sun W, Liu Y, Yang Y, et al. Status and related factors of postoperative recurrence of ovarian endometriosis: a cross-sectional study of 874 cases. Arch Gynecol Obstet. 2023; 307:1495–1501. doi: 10.1007/s00404-023-06932-x Yu O, Schulze-Rath R, Grafton MJ, Hansen MK, Scholes D, Reed SD. Adenomyosis incidence, prevalence and treatment: United States population-based study 2006–2015. Am. J. Obstet. Gynecol. 2020; 223:94.e1–94.e10. doi: 10.1016/j.ajog.2020.01.016.

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Outcome instruments

VAS-pain

Condition tags

endometriosisadenomyosischronic_pelvic_paindysmenorrheadyspareunia

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (16)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK