Mixed endometrioid and clear cell carcinoma arising from laparoscopic trocar site endometriosis

Tetsushi Tsuruga, Tetsuya Hirata, Ikumi Akiyama, Yōko Matsumoto, Yoko Matsumoto, Katsutoshi Oda, Tomoyuki Fujii, Yutaka Osuga
Journal of Obstetrics and Gynaecology Research · 2019 · vol. 45(8) , pp. 1613–1618 · doi:10.1111/jog.14014 · PMID:31183953 · W2952493732
article OA: closed CC0 ⤵ 12 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This case report describes a 49-year-old woman who developed mixed endometrioid and clear cell carcinoma arising from endometriosis at a laparoscopic trocar insertion site.

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Abstract

Laparoscopic port site endometriosis is less common in abdominal wall endometriosis, and malignant transformation of abdominal wall endometriosis is rare. We reported a case of mixed endometrioid and clear cell carcinoma arising from port site endometriosis. The patient was a 49-year-old woman with a history of laparoscopic excision of ovarian endometrioma. Physical examination revealed a subcutaneous solid tumor around the laparoscopic surgical scar. Imaging showed a suspicious malignancy. She underwent radical marginal resection of the abdominal wall tumor, flap reconstruction of the abdominal wall, hysterectomy, bilateral salpingo-oophorectomy and omental biopsy. Histological examination revealed mixed endometrioid and clear cell carcinoma. Computed tomography scan showed no evidence of recurrence after six cycles of chemotherapy. This is the first case of malignant transformation from laparoscopic trocar site endometriosis.

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Condition tags

endometriosisendometrioma

MeSH descriptors

Abdominal Neoplasms Abdominal Neoplasms Abdominal Neoplasms Abdominal Neoplasms Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Carcinoma, Endometrioid Carcinoma, Endometrioid Carcinoma, Endometrioid Carcinoma, Endometrioid Cell Transformation, Neoplastic Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Laparoscopy Ovarian Diseases

Citation neighborhood

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References (31)

Cited by (12)

Source provenance

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