Characterization of an ovarian carcinoma cell line
Lab / animal
public-domain-us
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This paper characterizes a long-term ovarian carcinoma cell line, detailing its morphology, electron microscopic features, and chromosomal abnormalities such as trisomy of multiple chromosomes and monosomy of 17 and 21.
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Abstract
A long-term ovarian carcinoma cell line is described in terms of its morphology, original histopathology, electron microscopic features and chromosome features before and after transplantation into an athymic nude mouse. The microscopic features of the tumor nodule grown in the nude mouse are compared with the original pathology. Epithelial characteristics of the cells were maintained in culture and after retrieval from the nude mouse. Three markers were identified in all karyotypes and trisomy was noted in chromosomes 1, 2, 3, 6, 11, 12, 16, and X and monosomy of 17 and 21.
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Cited by (2)
Cited by (2)
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- europepmc
- last seen: 2026-10-18T09:30:06.152893+00:00
- pubmed
- last seen: 2026-10-08T21:58:37.372514+00:00
License: public-domain-us
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· attribution required
Courtesy of the U.S. National Library of Medicine
Courtesy of the U.S. National Library of Medicine