Outcomes of Using Hormonal Therapy after Surgical Excision of Abdominal Wall Endometriomas

Raakad Kamel Saadi, Nabil I. Naiem, Mohammed Habash, M Bozkurt, A Cil, O Bozkurt, D Joly, H Harden, C Huguet, M Rd Blumenthal, Samoszuk, G Taylor, R Brown, Alisaroskas, Goldenberg, Aj Botha, J Halliday, Flanagan, T Ali, F Mohammed, R Hoford, D Maharaj, S Sookhoo, J Maillot, V Brun, M Dubuisson, N Bazot, Grenier, Cornelis, G Wolf, K Singh, Ns, L Nominato, I Prates, J Lauar, I Morais, S Maia, Gaber, Y Chang, E Tsai, C Long, Y Chen, N Kay, N Krawczyk, M Banys-Paluchowski, D Schmidt, U Ulrich, T Fehm, T Van Gorp, F Amant, P Neven, I Vergote, P Moerman, Y Ding, J Zhu, R Sirito, A Puppo, M Centurioni, C Gustavino, J Majeski, J Craggie, A Uysal, S Mun, G Eftaltaner, M Mistrangelo, N Gilbo, P Cassoni, S Micalef, R Faletti, C Miglietta, S Juneja, P Tandon, A Sharma, Rg, V Blanco, A Parithivel, M Shah, M Gumbs, P Schein, Gerst, Gk, G Patterson, Winburn, C Yu, M Peres-Reyes, J Brown, J Borella, Fc, D Medeiros, M Cavalcante, J Medeiros, Eleuterio, P Goel, L Devi, R Tandon, P Saha, A Dalal, Cp, A Barbosa, B Souza, D Bianco, F Christofolini, G Bach, Lima, E Oh, E Lee, J Kang, S Choi, K Kim, W Lee, Rs, S Purvis, Tyring, H Song, S Lee, M Kim, J Shin, D Lee, H Lee, A Hasan, A Deyab, Kh, A Monazea, Salem, S Marras, N Pluchino, P Petignat, J Wenger, F Ris, H Bumpers, K Butler, I Best, S Daye, J Barone, R Lincer, R Blabey, D Smego, Pfannenstiel Syndrome, C Teng, H Yang, K Chen, C Yang, L Chen, C Kuo, H Scholefield, Y Sajjad, P Morgan, X Zhao, H Lang, J Leng, Z Liu, P Wang, C Juang, H Chao, K Yu, C Yuan, H Ny, S Petakovic, P Perunicic, D Cuk
In: Journal of Pharmaceutical Negative Results · 2022 · vol. 13(3) · doi:10.47750/pnr.2022.13.03.161 · W4313034337
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This study compared surgical excision alone versus hormonal therapy after surgery for abdominal wall endometriosis, finding no difference in recurrence but reduced localized wound symptoms with hormonal therapy.

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Abstract

Endometriosis is a common gynecological pathology with the abdominal wall endometriosis (AWE) being a rarer one but with increasing frequency probably to the increased rate of deliveries by cesarean sections. Endometrial tissue is hormone responsive and its course of pathology can be directly influenced by hormonal therapy. The aim of the study is to evaluate the effect of using adjuvant hormonal therapy post-surgical excision of AWE regarding patient's wellbeing and the recurrence rate. We reviewed the records of our twenty (20) cases operated in a six (6) years period whom were or weren't subjected to postoperative hormonal therapy, comparing their follow up courses and recurrence rates.20 women in whom 18 women were multiparous (90%), mean age was 30.6years.the previous surgery was cesarean section in 19 patients (95%) with the main complaint as a cyclic pain and swelling at the site of previous surgery scar. The patients were divided in two groups 10 patients in each, group A included the patients who had surgery alone and group B for the patients who had hormonal therapy for nine months postsurgical excision. No recurrence was reported in each group, 60% of group A patients had localized pain and discomfort at the scar site which started six months post-surgery while this complaint wasn't recorded in any of group B patients. No difference was found in the recurrence rate between the two groups, absence of localized wound symptoms may indicate a better course and less future recurrence rate in the second group in the future. Some prophylactic methods are better to be taken seriously to decrease the rate of this complication.

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endometriosis

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